Evidence map›Paper›PMID 40534115›Full record

ArticleMagnetic resonance in medicine2025

High-density MRI coil arrays with integrated field monitoring systems for human connectome mapping.

Mirsad Mahmutovic, Manisha Shrestha, Gabriel Ramos-Llordén, Dongsuk Sung, Luke J Edwards, Ying Chu, Paul I Dubovan, Alina Müller, Sam-Luca J D Hansen, Anpreet Ghotra and 8 more

Abstract read
In one paragraph

Article in Magnetic resonance in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
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  4. ArXiv · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Mirsad MahmutovicInstitute of Medical Physics and Radiation Protection, TH-Mittelhessen University of Applied Sciences, Giessen, Hesse, Germany.ORCID https://orcid.org/0000-0001-9178-4194
Manisha ShresthaInstitute of Medical Physics and Radiation Protection, TH-Mittelhessen University of Applied Sciences, Giessen, Hesse, Germany.ORCID https://orcid.org/0009-0004-0066-4066
Gabriel Ramos-LlordénAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.ORCID https://orcid.org/0000-0003-4020-705X
Dongsuk SungAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Luke J EdwardsDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Saxony, Germany.ORCID https://orcid.org/0000-0002-8320-7298
Ying ChuDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Saxony, Germany.
Paul I DubovanAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Alina MüllerInstitute of Medical Physics and Radiation Protection, TH-Mittelhessen University of Applied Sciences, Giessen, Hesse, Germany.ORCID https://orcid.org/0000-0002-3324-6889
Sam-Luca J D HansenInstitute of Medical Physics and Radiation Protection, TH-Mittelhessen University of Applied Sciences, Giessen, Hesse, Germany.ORCID https://orcid.org/0000-0002-5353-5573
Anpreet GhotraInstitute of Medical Physics and Radiation Protection, TH-Mittelhessen University of Applied Sciences, Giessen, Hesse, Germany.ORCID https://orcid.org/0000-0001-6445-9062
Kerrin J PineDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Saxony, Germany.ORCID https://orcid.org/0000-0002-2486-2970
Roland MüllerNuclear Magnetic Resonance Methods and Development Group, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Saxony, Germany.
Nikolaus WeiskopfDepartment of Neurophysics, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Saxony, Germany.ORCID https://orcid.org/0000-0001-5239-1881
Lawrence L WaldAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Choukri MekkaouiAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Harald E MöllerNuclear Magnetic Resonance Methods and Development Group, Max Planck Institute for Human Cognitive and Brain Sciences, Leipzig, Saxony, Germany.ORCID https://orcid.org/0000-0002-5659-1925
Susie Y HuangAthinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Boston, Massachusetts, USA.
Boris KeilInstitute of Medical Physics and Radiation Protection, TH-Mittelhessen University of Applied Sciences, Giessen, Hesse, Germany.ORCID https://orcid.org/0000-0003-0805-8330

Funding

CONNECTOME 2.0: DEVELOPING THE NEXT GENERATION HUMAN MRI SCANNER FOR BRIDGING STUDIES OF THE MICRO-, MESO- AND MACRO-CONNECTOMEU01EB026996 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI BASSER, PETER J., HUANG, SUSIE YI · 2018 to 2022
$14.2M
Training and Dissemination CoreP41EB030006 · NIBIB · MASSACHUSETTS GENERAL HOSPITAL · PI Aapo Nummenmaa · 2020 to 2026
$10.9M
Connectome 2.0: A BRAIN Technology Integration and Dissemination Resource for Ultra-High Gradient Magnetic Resonance Imaging of Human Brain Circuits Across ScalesU24NS137077 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI Susie Yi Huang · 2024 to 2026
$4.0M
Revealing the Functional and Microstructural Response of Human Hippocampus to Spatial Learning with High-Gradient Strength Diffusion MRIK99NS132984 · NINDS · MASSACHUSETTS GENERAL HOSPITAL · PI RAMOS LLORDEN, GABRIEL · 2024 to 2025
$327k
Bundesministerium für Bildung und Forschung 01ED2210Deutsche Forschungsgemeinschaft 347592254 (WE 5046/4-2)Deutsche Forschungsgemeinschaft INST-169/22-1FP7 Ideas: European Research Council 616905Hessisches Ministerium für Wissenschaft und Kunst LOEWE/2/16/519/03/09.001(0001)/101Hessisches Ministerium für Wissenschaft und Kunst LOEWE/4TP/I519/05/02.002(0004)/107Horizon 2020 Framework Programme 681094NIBIB NIH HHS K99NS132984NIBIB NIH HHS P41 EB030006NIBIB NIH HHS P41-EB030006NIBIB NIH HHS U01 EB026996NIBIB NIH HHS U01-EB026996NIBIB NIH HHS U24-NS137077NINDS NIH HHS K99 NS132984NINDS NIH HHS U24 NS137077
6 · The paper itself

Abstract

purposeTo develop and test two high-density MRI coil arrays with integrated field monitoring systems for enhanced diffusion imaging with strong diffusion-sensitizing gradients.

methodsTwo multichannel head coils were constructed for first- and second-generation 3T Connectome MRI scanners, incorporating 64 and 72 receive channels, respectively. The array coils were evaluated using RF bench-level metrics, including quality factor, tuning, matching, and coupling measurements. Imaging performance was comprehensively assessed through metrics such as SNR,

resultsThe developed arrays demonstrated up to 1.4-fold higher SNR and superior g-factor performance when compared to a commercially available 32-channel head coil. Integration of the field camera was achieved without compromising the performance of either system. In vivo imaging with concurrent field monitoring enabled accurate spatiotemporal field corrections, significantly reducing geometric distortions, blurring, and ghosting in high

conclusionThe integration of high-density MRI arrays with field monitoring systems facilitated the capture and correction of spatiotemporal field perturbations during strong gradient activity, substantially enhancing image quality and diffusion parameter mapping quality. These advancements provide a robust platform for exploring the structural intricacies of the human connectome.

Indexed as

BrainConnectomeMagnetic Resonance ImagingDiffusion Magnetic Resonance ImagingEquipment DesignHumansImage Processing, Computer-AssistedPhantoms, ImagingSignal-To-Noise Ratiodiffusion MRIfield monitoringhuman connectome projectMRI radiofrequency coilphased array coil

Identifiers

PMID40534115
PMCPMC12393205

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.