Evidence map›Paper›PMID 40534099›Full record

ArticleJournal of cellular and molecular medicine2025

Diagnostic Use of CCR3, CD63, CD203c and FcεRIα on Blood Leukocytes of Allergic Asthma and Combined Allergic Rhinitis and Asthma Syndrome.

Junling Wang, Mengmeng Zhan, Fangqiu Gu, Huiyun Zhang, Hua Xie, Bingyu Qin, Shaoheng He

Abstract read
In one paragraph

Article in Journal of cellular and molecular medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. IL-18-associated basophil and mast cell activation in sepsis.Inflammation research : official journal of the European Histamine Research Society ... [et al.] · 2026
    Article
  2. [Allergens induce activation of blood CCR3Nan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Junling WangDepartment of Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.ORCID 0000-0002-4937-0665
Mengmeng ZhanDepartment of Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
Fangqiu GuAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.
Huiyun ZhangAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.ORCID 0000-0003-0631-3000
Hua XieThe PLA Center of Respiratory and Allergic Disease Diagnosing Management, General Hospital of Shenyang Military Area Command, Shenyang, Liaoning, China.
Bingyu QinDepartment of Critical Care Medicine, Henan Provincial People's Hospital, Zhengzhou University People's Hospital, Zhengzhou, Henan, China.
Shaoheng HeAllergy and Clinical Immunology Research Centre, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.

Funding

Foundation for Doctoral Scientific Research HN2022097Foundation for Doctoral Scientific Research ZC20230003Liaoning Province Science and Technology Planning Project 2021JH2/10300022National Natural Science Foundation of China 81471592National Natural Science Foundation of China 81472016Natural Science Foundation of Liaoning Province LJKZ0796This research was sponsored by the Key Research&Development and Promotion Special Foundation of Henan Province 232102311022
6 · The paper itself

Abstract

Altered basophil identification markers have been discovered to associate with allergic asthma (AA) recently. However, little is known of the expressions of basophil markers in blood granulocytes. We therefore parallel tested them in peripheral blood mononuclear cell (PBMC) and granulocyte populations of patients with AA and combined allergic rhinitis and asthma (ARA) by flow cytometry and assessed their diagnostic performance and examined plasma levels of EDN, LTC

Indexed as

AsthmaPhosphoric Diester HydrolasesPyrophosphatasesReceptors, CCR3Receptors, IgERhinitis, AllergicTetraspanin 30AdultBasophilsBiomarkersFemaleGranulocytesHumansLeukocytes, MononuclearMaleMiddle AgedBiomarkersCCR3 protein, humanCD63 protein, humanENPP3 protein, humanPhosphoric Diester HydrolasesPyrophosphatasesReceptors, CCR3Receptors, IgETetraspanin 30allergic asthmabasophilCCR3CD203ccombined allergic rhinitis and asthmaeosniophilgranulocyte

Identifiers

PMID40534099
PMCPMC12176697

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.