SynthesisHead & face medicine2025
The relationship between psychological factors and temporomandibular disorders: a systematic review and meta-analysis.
Synthesis in Head & face medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
27 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Efficacy of Myofascial Release Therapy and Related Soft-Tissue Techniques for Pain in Temporomandibular Disorders: A Systematic Review of Randomized Controlled Trials.Journal of oral rehabilitation · 2026Pooled it
- TENS/EMG-guided myocentric mandibular positioning: a systematic review and evidence map.Frontiers in oral health · 2026Pooled it
- Comparison of the Effects of Different Manual Therapy Techniques on Mandibular Mobility, Cervical Joint Position Sense, Jaw Function and Anxiety Levels in Individuals With Rheumatoid Arthritis and Temporomandibular Disorders: A Randomized Controlled Trial.Journal of oral rehabilitation · 2026Trial
- Comorbidities and associated factors of painful temporomandibular disorder symptoms in the BigMouth Dental Data Repository.Pain reports · 2026Article
- Screen use, health status, and self-perceived academic performance among Swedish dental and nursing students: an exploratory cross-sectional survey study.BMC medical education · 2026Article
- Temporomandibular disorders-related symptoms and associated comorbidities in children and adolescents: A BigMouth data repository cross-sectional study.Cranio : the journal of craniomandibular practice · 2026Article
- Psychometric Evidence on the Tampa Scale for Kinesiophobia for Temporomandibular Disorders: A Scoping Review.Dentistry journal · 2026Review
- Painful temporomandibular disorders, sleep bruxism, and anxiety symptoms in adolescents: a cross-sectional study.Odontology · 2026Article
- Temporomandibular disorders in children and adolescents: an underexplored condition in need of developmentally informed diagnostic guidance.Pain management · 2026Review
- Cross-cultural adaptation and psychometric validation of the Arabic version of the Orofacial Awakening Symptoms Questionnaire (OFASQ).Journal of oral & facial pain and headache · 2026Article
- Association Between Oral Behaviors and Symptoms of Anxiety and Depression in Romanian Adults Attending Private Dental Practices: A Cross-Sectional Observational Study.Journal of clinical medicine · 2026Article
- Oral Behaviors, Anxiety, and Depression in Temporomandibular Disorders: A Conceptual Narrative Review Within the DC/TMD Axis II Framework.Medicina (Kaunas, Lithuania) · 2026Review
- Latent profiles of oral health-related quality of life in temporomandibular disorders: implications for nurse-led stratified care.BMC nursing · 2026Article
- Article
- Psychological Features Associated With Awake Bruxism in Painful TMD: The Role of Anxiety.Journal of oral rehabilitation · 2026Article
- Psychological and somatosensory correlates of temporomandibular disorder: anxiety, somatosensory amplification, and coping strategies-a biopsychosocial perspective.Journal of oral & facial pain and headache · 2026Article
- Ultrasound examination of asymmetry in temporomandibular disorders.Clinics (Sao Paulo, Brazil) · 2026Article
- Association between primary Sjögren's disease and temporomandibular disorder in Taiwan: a 15-year nationwide cohort, with an exploratory analysis of hydroxychloroquine.BMC oral health · 2026Article
- Genetic subtraction reveals divergent pathways and targets in anxiety-related and anxiety-independent TMD.The journal of headache and pain · 2026Article
- Validity and reliability of the 8-item version of the jaw functional limitation scale (JFLS-8) in the Arabic language.Journal of oral & facial pain and headache · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
backgroundTemporomandibular disorders (TMD) are multifactorial conditions that involve pain, dysfunction, and impaired jaw movement, significantly impacting patients' quality of life. Emerging evidence suggests that psychological factors, including anxiety, depression, and stress, play a crucial role in the onset and progression of TMD. However, the exact nature of this relationship remains unclear. This study aims to systematically analyze and quantify the association between psychological factors and TMD, providing clinically relevant insights to improve patient management and therapeutic strategies.
methodsThis study was registered with the International Platform of Registered Systematic Review and Meta-Analysis Protocols (INPLASY202420084) to ensure methodological transparency and adherence to systematic review standards. The study design and protocol followed the Preferred Reporting of Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines. The National Institutes of Health (NIH) Quality Assessment Tool was used to assess the methodological quality of the included studies. The data were systematically extracted and analyzed.
resultsThe literature search yielded 2392 potential articles, of which 21 were included in this study. A significant correlation was found between TMD and anxiety, depression, stress, and somatization. Statistically significant differences in anxiety and depression scores were observed between patients with TMD and the controls (p < 0.00001). Stress increased TMD development and severity. In addition, subgroup analyses revealed gender differences, with depression significantly correlating with TMD in males. Similarly, students showed significant correlations between TMD and anxiety, while adults demonstrated strong associations with both anxiety and depression. Adolescents showed correlations between TMD development and somatization and obsessive-compulsiveness.
conclusionAnxiety, depression, and stress are significant risk factors for the development and progression of TMD. Subgroup analyses demonstrated significant correlations between particular psychological factors and TMD in different sub-populations.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.