Evidence map›Paper›PMID 40533798›Full record

SynthesisWorld journal of emergency surgery : WJES2025

The clinical efficacy and safety of ERCP in traumatic pancreatic injuries: a systematic review and meta-analysis.

Hulusi Can Karpuzcu, Çağdaş Erdoğan

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in World journal of emergency surgery : WJES, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Hulusi Can KarpuzcuDepartment of Gastroenterology, University of Health Sciences, Ankara Etlik City Hospital, Ankara, Turkey. can.karpuzcu@gmail.com.ORCID 0000-0002-2784-2027
Çağdaş ErdoğanDepartment of Gastroenterology, University of Health Sciences, Ankara Etlik City Hospital, Ankara, Turkey.ORCID 0000-0001-5903-6559

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTraumatic pancreatic injuries (TPI) are rare, critical complications increasingly managed by minimally invasive Endoscopic Retrograde Cholangiopancreatography (ERCP). We systematically reviewed and meta-analyzed ERCP's efficacy and safety for TPI regarding pancreatic duct integrity and clinical outcomes in diverse populations.

methodsPubMed, Scopus, Cochrane Library, and Web of Science were searched (2000-2024) for studies reporting on ERCP for TPI. Primary outcomes were pancreatic duct integrity and complications; secondary outcomes included mortality and hospital stay. Pediatric and adult populations were compared via subgroup analysis. Publication bias was assessed.

resultsFifteen studies comprising 1,823 patients (54% male, 32% pediatric) were included in the meta-analysis. ERCP demonstrated a pooled clinical success rate of 89% (95% CI: 83-93%) and significantly improved pancreatic duct integrity (OR for pancreatic duct integrity: 9.17, 95% CI: 6.73-12.49). Complication rates ranged from 4 to 17%, with pancreatitis and bleeding being the most common adverse events. Mortality rates were low (3-5%), and ERCP significantly reduced hospital stay by an average of 3.1 days compared to surgical interventions. Pediatric patients had slightly lower success rates (OR: 6.73, 95% CI: 4.01-11.31) compared to adults (OR: 10.87, 95% CI: 7.40-15.98).

conclusionsERCP is an effective and safe modality for managing TPI in both pediatric and adult patients, yielding high success rates in maintaining ductal integrity and reducing complications, although interpretation requires caution due to potential publication bias. Further prospective studies are required to optimize standardized protocols.

Indexed as

Cholangiopancreatography, Endoscopic RetrogradePancreasHumansTreatment OutcomeEndoscopic retrograde cholangiopancreatographyMeta-analysisPancreatic duct injuryTraumaTraumatic pancreatic injury

Identifiers

PMID40533798
PMCPMC12178067

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.