Evidence map›Paper›PMID 40533661›Full record

ArticleEJNMMI research2025

Characterization of in vivo binding kinetics and non-displaceable binding of [

Catriona Wimberley, Carlos J Alcaide-Corral, Timaeus E F Morgan, Mark G Macaskill, Bernadette Andrews, Holly McErlain, Valeria K Burianova, Andrew Sutherland, Adriana A S Tavares

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in EJNMMI research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Catriona WimberleySchool of Physics and Astronomy, University of Edinburgh, Edinburgh, United Kingdom.
Carlos J Alcaide-CorralEdinburgh Imaging, University of Edinburgh, Edinburgh, United Kingdom.
Timaeus E F MorganEdinburgh Imaging, University of Edinburgh, Edinburgh, United Kingdom.
Mark G MacaskillEdinburgh Imaging, University of Edinburgh, Edinburgh, United Kingdom.
Bernadette AndrewsSchool of Physics and Astronomy, University of Edinburgh, Edinburgh, United Kingdom.
Holly McErlainSchool of Chemistry, University of Glasgow, Glasgow, United Kingdom.
Valeria K BurianovaSchool of Chemistry, University of Glasgow, Glasgow, United Kingdom.
Andrew SutherlandSchool of Chemistry, University of Glasgow, Glasgow, United Kingdom.
Adriana A S TavaresEdinburgh Imaging, University of Edinburgh, Edinburgh, United Kingdom. adriana.tavares@ed.ac.uk.ORCID http://orcid.org/0000-0001-7505-9144

Funding

British Heart Foundation FS/19/34/34354British Heart Foundation RE/13/3/30183British Heart Foundation RG/16/10/32375British Heart Foundation RG/F/22/110093Chan Zuckerberg Initiative DAF2021-225273Engineering and Physical Sciences Research Council EP/T517896/1Wellcome TrustWellcome Trust 221295/Z/20/Z
6 · The paper itself

Abstract

backgroundThe synaptic vesicle glycoprotein 2 A (SV2A) has been identified as a biomarker of interest for neurological pathology. The SV2A specific radiotracer [

resultsThe pharmacokinetics of [

conclusion[ CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

[18F]SynVesT-1Mass dosePreclinical PETRatSV2A

Identifiers

PMID40533661
PMCPMC12176722

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.