Evidence map›Paper›PMID 40533648›Full record

SynthesisCurrent obesity reports2025

Additional Effect of Exercise to Intermittent Fasting on Body Composition and Cardiometabolic Health in Adults With Overweight/obesity: A Systematic Review and Meta-analysis.

Zi-Han Dai, Ke-Wen Wan, Po-San Wong, Wendy Yajun Huang, Angus Pak-Hung Yu, Stephen Heung-Sang Wong

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Current obesity reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Zi-Han DaiDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Ke-Wen WanAcademy of Wellness and Human Development, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
Po-San WongDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Wendy Yajun HuangAcademy of Wellness and Human Development, Hong Kong Baptist University, Kowloon Tong, Hong Kong, China.
Angus Pak-Hung YuDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin, Hong Kong, China.
Stephen Heung-Sang WongDepartment of Sports Science and Physical Education, The Chinese University of Hong Kong, Shatin, Hong Kong, China. hsswong@cuhk.edu.hk.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThe purpose of this study is to evaluate the additional effect of exercise to intermittent fasting (IF) on body composition and cardiometabolic health in adults with overweight/obesity.

methodRelevant studies were identified through a systematic search across five databases. A random-effects meta-analysis was conducted on outcomes including body composition and cardiometabolic health markers, to compare the effect of combining IF with exercise against IF alone. The certainty of the evidence was evaluated using the GRADE approach, while the quality of the included studies was assessed using the revised Cochrane risk-of-bias tool and the TESTEX scale.

resultIn total, twelve studies including 616 participants (Age: 40 ± 9 years; BMI: 33.6 ± 4.8 kg/m

conclusionThe potential benefits of incorporating exercise into IF for adults with overweight/obesity, particularly in terms of body composition, glycemic control, and cardiorespiratory fitness, appear promising. Nevertheless, given the limited amount of data, future investigations are essential to strengthen the evidence base and investigate the influence of specific exercise and IF types in enhancing treatment outcomes. Registry and registry number for systematic reviews or meta-analyses: CRD42024550753.

Indexed as

Body CompositionExerciseExercise TherapyFastingObesityOverweightAdultFemaleHumansIntermittent FastingMaleMiddle AgedBody compositionCardiometabolic healthExerciseIntermittent fastingMeta-analysisOverweight/Obesity

Identifiers

PMID40533648
PMCPMC12176969

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.