Evidence map›Paper›PMID 40533602›Full record

Observational studyEuropean journal of orthopaedic surgery & traumatology : orthopedie traumatologie2025

Periprosthetic femur fractures of the hip in elderly patients: early surgery reduces operative time, hospitalization, and mortality.

Domenico De Mauro, Giacomo Capece, Marcello Covino, Andrea Russo, Sara Salini, Omar El Ezzo, Francesco Bosco, Giulio Maccauro, Raffele Vitiello

Abstract readObservational Study
PubMed Publisher
In one paragraph

Observational study in European journal of orthopaedic surgery & traumatology : orthopedie traumatologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Outcome of surgical fixation of interprosthetic femur fractures: a case series in a district general hospital.European journal of orthopaedic surgery & traumatology : orthopedie traumatologie · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Domenico De MauroDepartment of Orthopaedics and Traumatology, Catholic University of the Sacred Heart, Milan, Italy.
Giacomo CapeceDepartment of Orthopaedics and Traumatology, Catholic University of the Sacred Heart, Milan, Italy.
Marcello CovinoDepartment of Emergency Medicine, Fondazione Policlinico Universitario A. Gemelli IRCCS, Largo Agostino Gemelli, 8, 00168, Rome, Italy.
Andrea RussoDepartment of Orthopaedics and Traumatology, University of Naples Federico II, Naples, Italy.
Sara SaliniDepartment of Orthopaedics and Traumatology, University of Naples Federico II, Naples, Italy.
Omar El EzzoDepartment of Orthopedics, Ageing and Rheumatological Sciences, Fondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Francesco BoscoDepartment of Precision Medicine in Medical, Surgical and Critical Care (Me.Pre.C.C.), University of Palermo, Palermo, Italy. francesco.bosco03@unipa.it.
Giulio MaccauroDepartment of Orthopaedics and Traumatology, Catholic University of the Sacred Heart, Milan, Italy.
Raffele VitielloDepartment of Orthopaedics and Traumatology, Catholic University of the Sacred Heart, Milan, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPeriprosthetic femur fractures around the hip represent a significant clinical challenge, particularly in patients aged 65 and older, as delayed treatment can lead to increased morbidity and mortality. Early surgical intervention is generally recommended to minimize complications and optimize functional recovery. This study aims to assess the impact of surgical timing on operative duration, hospitalization length, complication rates, and long-term survival in elderly patients with periprosthetic femur fractures.

methodsA retrospective observational study followed STROBE guidelines and the Declaration of Helsinki. Patients aged ≥ 65 years with periprosthetic femur fractures treated surgically between 2014 and 2022 were included. Patients were stratified into two groups based on surgical timing: Early Surgery (< 24 h) and Delayed Surgery (≥ 24 h). Frailty was assessed using the Clinical Frailty Scale, while medical condition severity was evaluated with the National Early Warning Score. Primary outcomes included operative time, hospitalization length, complications, and survival. Statistical analyses were performed using t-tests, chi-squared tests, and Kaplan-Meier survival analysis, with significance at p < 0.05.

resultsSeventy-two patients were analyzed. The mean operative time was significantly shorter in the Early Surgery group (145 ± 49.6 min) compared to the Delayed Surgery group (176 ± 71.9 min; p < 0.001). Hospitalization duration was also reduced in the Early Surgery group (12.1 ± 5.98 days vs. 19.7 ± 13.2 days; p = 0.002). Survival analysis demonstrated significantly better long-term outcomes in the Early Surgery group (p = 0.036), with 10-year survival rates of 92.8% versus 68.2%.

conclusionEarly surgical intervention (< 24 h) in elderly patients with periprosthetic femur fractures is associated with shorter operative time, reduced hospitalization, and improved long-term survival compared to delayed surgery. Prompt surgical management should be prioritized to enhance patient outcomes.

Indexed as

Arthroplasty, Replacement, HipFemoral FracturesHip FracturesOperative TimePeriprosthetic FracturesTime-to-TreatmentAgedAged, 80 and overFemaleHospitalizationHumansLength of StayMalePostoperative ComplicationsRetrospective StudiesElderlyFrailtyHip fracturesPeriprosthetic fractureTotal hip arthroplasty

Identifiers

PMID40533602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.