Evidence map›Paper›PMID 40533597›Full record

ArticleDiscover oncology2025

Publication trends and hotspots for cervical cancer screening biomarker: a bibliometric analysis.

Jia Xu, Wen Yang, Liangying Liu, Shuting Zhou, Xiangshu Jin, Min Zhao, Miao Liu, Yuanguang Meng

Abstract read
In one paragraph

Article in Discover oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jia Xu *Department of Obstetrics and Gynecology, The Seventh Medical Center of Chinese PLA General Hospital, Beijing, China.
Wen Yang *Department of Obstetrics and Gynecology, The Seventh Medical Center of Chinese PLA General Hospital, Beijing, China.
Liangying Liu *Library of Graduate School, Chinese PLA General Hospital, Beijing, China.
Shuting ZhouDepartment of Obstetrics and Gynecology, The Seventh Medical Center of Chinese PLA General Hospital, Beijing, China.
Xiangshu JinDepartment of Obstetrics and Gynecology, The Seventh Medical Center of Chinese PLA General Hospital, Beijing, China.
Min ZhaoDepartment of Gastroenterology, The Second Medical Center of Chinese PLA General Hospital, Beijing, China.
Miao LiuGraduate School, Chinese PLA General Hospital, Beijing, China. liumiaolmbxb@163.com.
Yuanguang MengDepartment of Obstetrics and Gynecology, The Seventh Medical Center of Chinese PLA General Hospital, Beijing, China. meng6512@vip.sina.com.

Funding

the Chinese PLA military family planning project 22JSZ16
6 · The paper itself

Abstract

backgroundThe global disease burden of cervical cancer has remained significant throughout history. It is essential to discover sensitive and specific biomarkers for cervical cancer screening to enhance its quality and efficiency. This study aimed to delineate the publication trends and hotspots for cervical cancer screening biomarker through a bibliometric analysis. Therefore, researchers could acquire a comprehensive understanding of this area.

methodsProfessional search strategies were employed to collect literatures, with the central keywords being cervical cancer screening biomarker. Publications were retrieved from CBM/CNKI/Wanfang databases in Chinese and WoSCC/Pubmed databases in English. After being reviewed by two researchers, the publication dataset was analyzed in terms of sources, countries, authors, journals, citations and keywords using Citespace and bibliometrix package in the R environment.

results547 publications of Chinese origin and 1068 of English origin were picked out. China, the USA and the Netherlands were the most contributing countries. Professor Meijer was the most outstanding author. There is a need to publish articles on our targeted topic in journals with greater academic influence. Current published literatures predominately focused on "p16(ink4a) protein", "DNA methylation" and "human papillomavirus". It has been popular in recent years to identify hub genes as candidate biomarkers through bioinformatics analysis.

conclusionsIt is a challenge to discover a novel and convenient biomarker to simplify the cervical cancer screening process. Global collaboration and clinical trials in high-incidence countries may contribute to the advancement of biomarker research. HPV testing, p16(ink4a) protein and DNA methylation used to be research hotspots, and they are now applied in clinical practice. Cervico-vaginal microbiota and bioinformatics analysis are the new keywords that have emerged recently.

Indexed as

BibliometricsBiomarkerCervical cancerScreening

Identifiers

PMID40533597
PMCPMC12177119

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.