ArticleNature immunology2025
CARD11 signaling regulates CD8
Abstract read
In one paragraph
Article in Nature immunology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.
0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
9 citing papers in PubMed.
- Chemo-metallo nanodrivers for spatiotemporally controlled in situ vaccination.Science advances · 2026Article
- The ADAP-TRIM21-ZEB2 axis regulates CD8iScience · 2026Article
- Prognostic Significance and Immune Landscape of Neuroendocrine Differentiation-Related Genes in Non-Small Cell Lung Cancer.Biological procedures online · 2026Article
- Upregulation of TCF1 and BCL11B in CD8+ effector T cells predicts favorable response to ibrutinib in patients with chronic lymphocytic leukemia.Communications biology · 2026Article
- Optimizing patient selection for neoadjuvant immunotherapy in gastric cancer via pre-treatment imaging analysis.Frontiers in immunology · 2026Article
- Potentiation of noncanonical NF-κB signaling and marginal zone B cell expansion by CARD11-mediated regulation of p100 processing.Cell reports · 2025Article
- Development of a prognostic risk model for colorectal cancer based on microsatellite stability-associated genes.BMC cancer · 2025Article
- Multimodal cell-cell communication driving CD8Frontiers in immunology · 2025Review
- CD82-associated exhausted CD8Frontiers in immunology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
16 authors.
Yu Hu *Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0002-5081-7989
Qifan Zhao *Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0000-0002-6764-0489
Yingquan Qin *Shanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.ORCID http://orcid.org/0009-0007-9129-8621
Song Mei *Shanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.ORCID http://orcid.org/0009-0005-0426-2467
Benyu WangShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Haoyue ZhouShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Linli HanDepartment of Clinical Immunology, Children's Hospital of Fudan University, National Children's Medical Center, Shanghai, China.
Yi ZangShanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Liangjiao YaoShanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Zhe HeShanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China.
Yingyi LiDepartment of Thoracic Surgery, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hecheng LiCenter for Immune-related Diseases at Shanghai Institute of Immunology, Ruijin Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China. lihecheng2000@hotmail.com.ORCID http://orcid.org/0000-0001-8069-6033
Peng ZhangBeijing Key Laboratory for Genetics of Birth Defects, Beijing Pediatric Research Institute, MOE Key Laboratory of Major Diseases in Children; Rare Disease Center, Beijing Children's Hospital, Capital Medical University, National Center for Children's Health, Beijing, China. zhangpengdyx@163.com.ORCID http://orcid.org/0000-0002-6218-1885
Yan ZhangShanghai Institute of Immunology, Department of Immunology and Microbiology, Shanghai Jiao Tong University School of Medicine, Shanghai, China. zhy3331a@shsmu.edu.cn.ORCID http://orcid.org/0000-0002-6962-8782
Michael J LenardoMolecular Development of the Immune System Section, Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. lenardo@nih.gov.ORCID http://orcid.org/0000-0003-1584-468X
Wei LuShanghai Institute of Nutrition and Health, University of Chinese Academy of Sciences, Chinese Academy of Sciences, Shanghai, China. lvwei@sinh.ac.cn.ORCID http://orcid.org/0000-0002-2391-5444
Funding
National Natural Science Foundation of China (National Science Foundation of China) 82050001National Natural Science Foundation of China (National Science Foundation of China) 82072557National Natural Science Foundation of China (National Science Foundation of China) 82241227National Natural Science Foundation of China (National Science Foundation of China) 82271762National Natural Science Foundation of China (National Science Foundation of China) 82330051National Natural Science Foundation of China (National Science Foundation of China) 82372855National Natural Science Foundation of China (National Science Foundation of China) 92478203
Abstract
Chronic stimulation in the tumor microenvironment can induce exhausted CD8
Indexed as
CARD Signaling Adaptor ProteinsCD8-Positive T-LymphocytesGuanylate CyclaseNeoplasmsSignal TransductionAnimalsCell DifferentiationCell Line, TumorCytotoxicity, ImmunologicHumansMiceMutationReceptors, Antigen, T-CellTumor MicroenvironmentCARD11 protein, humanCARD Signaling Adaptor ProteinsGuanylate CyclaseReceptors, Antigen, T-Cell
Identifiers
PMID
40533509What OpenQuestion holds
Textmetadata
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.