Evidence map›Paper›PMID 40533256›Full record

ArticleThe British journal of general practice : the journal of the Royal College of General Practitioners2025

Temporal trends in primary care-recorded psychiatric diagnoses and psychotropic medication prescribing among children and young people in the UK: a population-based study.

Alex M Trafford, Matthew J Carr, Darren M Ashcroft, Carolyn A Chew-Graham, Emma Cockcroft, Lukasz Cybulski, Emma Garavini, Shruti Garg, Louise Hussey, Thomas Kabir and 4 more

Abstract read
In one paragraph

Article in The British journal of general practice : the journal of the Royal College of General Practitioners, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Alex M TraffordCentre for Pharmacoepidemiology & Drug Safety, Division of Pharmacy & Optometry, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.ORCID 0000-0001-8145-8133
Matthew J CarrCentre for Pharmacoepidemiology & Drug Safety, Division of Pharmacy & Optometry, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.ORCID 0000-0001-7336-1606
Darren M AshcroftCentre for Pharmacoepidemiology & Drug Safety, Division of Pharmacy & Optometry, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.ORCID 0000-0002-2958-915X
Carolyn A Chew-GrahamNIHR Greater Manchester Patient Safety Research Collaboration, University of Manchester, Manchester, UK.ORCID 0000-0002-9722-9981
Emma CockcroftDepartment of Health & Community Sciences, University of Exeter, Exeter, UK.ORCID 0000-0003-3798-9492
Lukasz CybulskiDivision of Insurance Medicine, Karolinska Institutet, Stockholm, Sweden.ORCID 0000-0002-1774-7288
Emma GaraviniMcPin Foundation, London, UK.ORCID 0000-0003-2067-3838
Shruti GargDivision of Psychology & Mental Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.ORCID 0000-0002-4472-4583
Louise HusseyDivision of Psychology & Mental Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.ORCID 0000-0001-6108-5085
Thomas KabirDepartments of Experimental Psychology & Psychiatry, University of Oxford, Oxford, UK.ORCID 0000-0001-8908-0964
Nav KapurNIHR Greater Manchester Patient Safety Research Collaboration, University of Manchester, Manchester, UK.ORCID 0000-0002-3100-3234
Rachel K TempleMcPin Foundation, London, UK.ORCID 0000-0002-3126-5701
Roger T WebbNIHR Greater Manchester Patient Safety Research Collaboration, University of Manchester, Manchester, UK.ORCID 0000-0001-8532-2647
Pearl Lh MokCentre for Pharmacoepidemiology & Drug Safety, Division of Pharmacy & Optometry, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK pearl.mok@manchester.ac.uk.ORCID 0000-0001-9983-6374

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundDespite growing concerns about young people's mental health, it remains unclear how rates of psychiatric diagnoses and psychotropic medication prescribing have changed.

aimTo investigate temporal trends in UK primary care-recorded incidence of (1) psychiatric diagnoses: attention deficit hyperactivity disorders (ADHD), autism spectrum conditions, anxiety disorders, depression, substance misuse, and personality disorders, and (2) psychotropic medication prescribing, in individuals aged 1-24 years. DESIGN AND

settingThis was a population-based study using primary care data from the Clinical Practice Research Datalink.

methodThe monthly incidence of each outcome from January 2010 to March 2022 were calculated. Negative binomial regression was used to predict expected incidence rates when the COVID-19 pandemic began in March 2020, based on antecedent trends. Observed and predicted (that is, expected) rates were compared.

resultsIn the 2 years following March 2020, the incidence of ADHD diagnoses in females was 24.7% (95% confidence interval = 11.9 to 38.9%) greater than the expected incidence rate predicted from the trends before the pandemic. The increase in ADHD diagnoses occurred more commonly for females aged 20-24 years, followed by those aged 17-19 years, as well as among females from less deprived areas. Similar trends were observed for ADHD medications. Observed rates of other outcomes, including common mental illnesses, were below or close to the expected levels, with the differentials between observed and expected rates being greater for males than females.

conclusionIncreased ADHD awareness may partly explain the study's findings. However, the fall in other diagnoses may reflect barriers to accessing health services at the height of the pandemic. Early identification and timely treatment of mental health difficulties and neurodevelopmental conditions are crucial.

Indexed as

Drug PrescriptionsMental DisordersPractice Patterns, Physicians'Primary Health CarePsychotropic DrugsAdolescentChildChild, PreschoolCohort StudiesElectronic Health RecordsFemaleHumansIncidenceInfantMaleUnited KingdomPsychotropic DrugsADHDCOVID-19mental healthpatient involvementprimary health care

Identifiers

PMID40533256
PMCPMC12723501

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.