ArticleClinical and translational allergy2025
Self-reported accidental allergic reactions among patients with challenge-verified food allergy.
Article in Clinical and translational allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Self-reported accidental allergic reactions among patients with challenge-verified food allergy.Clinical and translational allergy · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundFood allergy affects up to 6% of the population and emergency department visits due to accidental food-allergic reactions are increasing. This study evaluated accidental allergic reactions outside the hospital and the number of hospitalizations in food allergic patients as well as the pattern before and after the diagnosis of food allergy by oral food challenge (OFC).
methodsAn electronic questionnaire concerning accidental allergic reactions was sent to 785 patients with challenge verified peanuts, hazelnuts, cow's milk and/or hen's egg allergies at the Allergy Centre, Odense University Hospital, Denmark.
resultsIn total, 51% (402/785) responded. Among the 357 who reported at least one accidental allergic reaction, 51.5% (184/357) reported a total of six or less reactions, whereas 22.4% (80/357) had experienced a total of ≥21 reactions. Skin symptoms were commonly reported by children/adolescents (n = 277), whereas symptoms from all other organ systems were more frequently reported by adults (n = 80). In total, 61.6% (220/357) experienced at least one accidental allergic reaction, requiring immediate medical attention, which decreased from 77.3% (170/220) before to 55% (121/220) after establishment of the food allergy diagnosis by OFC. A concomitant proportional increase in the number of hospitalizations was identified (63.5% (108/170) to 72.7% (88/121)). LIMITATIONS: We had no exact data on the timing of the accidental allergic reactions for the individual allergens.
conclusionAccidental food-allergic reactions are common and often severe. After the diagnostic OFC, the number of patients with reactions decreased, and the proportion of hospitalizations increased, indicating improved disease and healthcare management.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.