Evidence map›Paper›PMID 40532746›Full record

ArticleAlcohol (Fayetteville, N.Y.)2025

Associations of physical pain, alcohol use, and related factors in the daily lives of patients with chronic low back pain.

Ian A McNamara, Jeff Boissoneault, Jarrod M Ellingson, Jake Sauer, Ryan W Carpenter

Abstract read
In one paragraph

Article in Alcohol (Fayetteville, N.Y.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The role of distress tolerance in the momentary relationship between negative affect and drinking in daily life.Psychology of addictive behaviors : journal of the Society of Psychologists in Addictive Behaviors · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ian A McNamaraDepartment of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA. Electronic address: imcnamar@nd.edu.
Jeff BoissoneaultDepartment of Anesthesiology, University of Minnesota, Minneapolis, MN 55455, USA.
Jarrod M EllingsonDepartment of Psychiatry, University of Colorado - Anschutz Medical Campus, Aurora, CO 80045, USA; Institute for Behavioral Genetics, University of Colorado - Boulder, CO 80309, USA.
Jake SauerDepartment of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA.
Ryan W CarpenterDepartment of Psychology, University of Notre Dame, Notre Dame, IN 46556, USA.

Funding

Common mechanisms of the microbiota-gut-brain axis in alcohol use disorder and depression: A genetically informed investigationK23AA026635 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI ELLINGSON, JARROD MARTIN · 2018 to 2022
$907k
Developing a modified brief alcohol-focused intervention tailored for patients with alcohol use disorder in opioid agonist treatmentK23AA029729 · NIAAA · UNIVERSITY OF NOTRE DAME · PI Ryan W Carpenter · 2022 to 2026
$793k
Ambulatory assessment of physical pain, emotional distress and alcohol useF31AA023447 · NIAAA · UNIVERSITY OF MISSOURI-COLUMBIA · PI CARPENTER, RYAN W · 2015 to 2016
$70k
NIAAA NIH HHS F31 AA023447NIAAA NIH HHS K23 AA026635NIAAA NIH HHS K23 AA029729
6 · The paper itself

Abstract

backgroundAlcohol use and chronic pain are highly prevalent, costly, and have a bidirectional relationship. This may occur, in part, because of the analgesic effects of alcohol. Specifically, individuals may drink alcohol to address both physical pain and the subsequent increases in negative affect that may be brought on by painful experiences. The current project examined the Catastrophizing, Anxiety, Negative Urgency, and Expectancy (CANUE) model in daily life to better understand the association between alcohol use and pain.

methodsHypothesized paths of the CANUE model were examined using intensive longitudinal data (n = 34; total n

resultsPrevious-occasion physical pain, but not cumulative-average pain, and pain-related alcohol expectancies, were associated with a greater likelihood of alcohol use. Though there was no main effect of cumulative-average negative affect on alcohol use, negative affect interacted with impulsivity, such that participants were more likely to continue drinking when experiencing increased negative affect and impulsivity. Results did not find a hypothesized indirect effect of pain on alcohol use via negative affect. Alcohol use was associated with reduced next-occasion pain and increased perceptions of alcohol-related pain relief. DISCUSSION: While cumulative-average pain was not associated with an increased likelihood of drinking, individuals were more likely to drink after occasions of elevated pain. This may indicate that participants drank to reduce pain, as was also suggested by the association between pain-related alcohol expectancies and drinking. This is one of the first studies to examine associations of alcohol use and chronic pain in daily life. The results provide evidence for the importance of pain as an antecedent to alcohol use. Findings supported some components of the CANUE model but also highlight the need for further investigation to inform potential revision of the mode.

Indexed as

Alcohol DrinkingChronic PainLow Back PainAdultAnxietyCatastrophizationEcological Momentary AssessmentFemaleHumansLongitudinal StudiesMaleMiddle AgedAlcohol useCANUE modelChronic painEMA

Identifiers

PMID40532746
PMCPMC12788169

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.