ArticleFetal diagnosis and therapy2025
Left and Right Ventricular Strain Mechanics in Fetal Tachyarrhythmia.
Article in Fetal diagnosis and therapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
<p>Introduction: Assessment of myocardial function in fetuses with supraventricular tachyarrhythmia is challenging. Speckle-tracking echocardiography (STE) is a newer sensitive method to assess ventricular systolic function. We sought to assess left (LV) and right (RV) ventricular myocardial strain mechanics in fetuses with tachyarrhythmia and hypothesized that strain mechanics are impaired in this patient population even after conversion to sinus rhythm.
methodsThis was a single-center retrospective review. LV and RV strain parameters were assessed using STE in tachyarrhythmia and after conversion to sinus rhythm and, compared to gestational age (GA), matched control fetuses in sinus rhythm.
resultsEighteen fetuses with tachyarrhythmia and 18 controls were analyzed at median GA of 31 weeks (range 28-34 weeks). LV Global Longitudinal Strain (GLS) (-4.5% [-5.2, -1.9] vs. -11.2% [-14.6, -9.9]; p value 0.0001), Strain Rate (-0.8% [-1.5, -0.6] vs. -1.7% [-2.5, -1.2]; p value 0.007), and Global Longitudinal Velocity (GLV) (0.7 cm/s [0.5, 1.3] vs. 1.8 cm/s [0.9, 2.1]; p value 0.003) were reduced in tachyarrhythmia and improved with sinus rhythm but remained abnormal compared to controls. RV GLS (-6.3% [-8.5, -5.1] vs. -13.6% [-15.3, -10.6]; p value <0.0001), Strain rate (-1.3% [-1.7, -0.9] vs. -2.1% [-2.5, -1.4]; p value 0.0103), and GLV (1.2 cm/s [0.8, 1.7] vs. 1.9 cm/s [1.2, 2.7]; p value 0.026) were low in tachyarrhythmia and improved with sinus rhythm but remained lower than in controls. Regional strain was decreased in all LV and RV segments in tachyarrhythmia.
conclusionFetuses in tachyarrhythmia had reduced measures of myocardial deformation that improved with sinus rhythm but remained low compared to matched controls. Future studies are needed to explore the utility of STE for serial monitoring of fetuses in tachyarrhythmia and to assess response to therapy. </p>.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.