Evidence map›Paper›PMID 40532091›Full record

Trial reportAmerican journal of speech-language pathology2025

Interim Treatment Fidelity for a Randomized Controlled Comparative Effectiveness Trial of Two Variants of Semantic Feature Analysis Treatment for Aphasia.

Miranda C Babiak, William D Hula, Alyssa Autenreith, Mary M Nader, Shannon Austermann Hula, Alexander Swiderski, Robert Cavanaugh, Kristen Nunn, Jeffrey P Johnson, Michael Walsh Dickey

Abstract readRandomized Controlled TrialComparative Study
In one paragraph

Trial report in American journal of speech-language pathology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Miranda C BabiakAudiology and Speech Pathology Service, VA Pittsburgh Healthcare System, PA.ORCID 0009-0001-5580-3201
William D HulaAudiology and Speech Pathology Service, VA Pittsburgh Healthcare System, PA.ORCID 0000-0003-1635-0753
Alyssa AutenreithAudiology and Speech Pathology Service, VA Pittsburgh Healthcare System, PA.
Mary M NaderAudiology and Speech Pathology Service, VA Pittsburgh Healthcare System, PA.
Shannon Austermann HulaAudiology and Speech Pathology Service, VA Pittsburgh Healthcare System, PA.
Alexander SwiderskiAudiology and Speech Pathology Service, VA Pittsburgh Healthcare System, PA.ORCID 0000-0001-7438-8667
Robert CavanaughObservational Health Data Sciences and Informatics Center, Roux Institute, Northeastern University, Portland, ME.ORCID 0000-0002-2114-6565
Kristen NunnAudiology and Speech Pathology Service, VA Pittsburgh Healthcare System, PA.ORCID 0000-0002-9562-7185
Jeffrey P JohnsonAudiology and Speech Pathology Service, VA Pittsburgh Healthcare System, PA.
Michael Walsh DickeyAudiology and Speech Pathology Service, VA Pittsburgh Healthcare System, PA.ORCID 0000-0002-9068-3313

Funding

Optimizing and understanding semantic feature analysis treatment for aphasia: A randomized controlled comparative-effectiveness trialR01DC017475 · NIDCD · VETERANS HEALTH FOUNDATION · PI DICKEY, MICHAEL WALSH, DOYLE, PATRICK J. · 2019 to 2023
$2.6M
Stuttering in the real world: Quantifying variability to improve measurement reliability and validityR01DC018795 · NIDCD · MICHIGAN STATE UNIVERSITY · PI YARUSS, J. SCOTT · 2020 to 2024
$2.2M
NIDCD NIH HHS R01 DC017475NIDCD NIH HHS R01 DC018795
6 · The paper itself

Abstract

purposeThis study evaluated treatment fidelity for an ongoing randomized controlled trial comparing two variants of semantic feature analysis (SFA) treatment for naming impairment in aphasia. In this trial, participants are being randomized to treatment conditions (many- or few-features) in which they are asked to generate either 11 or five features per SFA trial.

methodTreatment fidelity was addressed via study design, manualization of the treatment, provider training, and maintenance of daily treatment logs, among other approaches. Fidelity was assessed through protocol adherence checks, interrater reliability of feature counting, and analysis of treatment dosage. Protocol adherence was measured using a 20-item checklist. Interrater reliability was evaluated for feature counts on 10% of treatment sessions. Treatment dosage was analyzed to confirm differentiation between many-features and few-features groups in terms of features generated and exposed and equivalence in terms of total treatment time.

resultsOverall protocol adherence was 99%. Interrater reliability for feature counting showed good-to-excellent agreement. Analysis of treatment dosage in terms of features per trial confirmed clear differentiation between groups, with the many-features group generating or being exposed to approximately 10-11 features per trial compared to four to five features for the few-features group. Analysis of other aspects of dosage also suggested good fidelity to the design.

conclusionsThis ongoing trial of SFA is being implemented with high levels of treatment fidelity. The study demonstrates the importance and feasibility of comprehensive fidelity monitoring in aphasia treatment research. Detailed fidelity procedures and outcomes support interpretation, replication, and clinical implementation of study findings. SUPPLEMENTAL MATERIAL: https://doi.org/10.23641/asha.29230937.

Indexed as

AphasiaLanguage TherapySemanticsComparative Effectiveness ResearchFemaleHumansMaleMiddle AgedReproducibility of ResultsTreatment Outcome

Identifiers

PMID40532091
PMCPMC12270838

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.