Evidence map›Paper›PMID 40531960›Full record

ArticleScience robotics2025

Preventing pressure ulcers by increasing pressure: An unorthodox alternating-pressure mattress.

Zhidi Yang, James L Weida, Siyuan Shao, Brandon Reedel, Collin Shannon, Junlin Chen, Piyush Sheth, Jonathan B Hopkins

Abstract read
In one paragraph

Article in Science robotics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zhidi YangMechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0009-0009-5420-6673
James L WeidaMechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0009-0008-6400-5755
Siyuan ShaoMechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Brandon ReedelMechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0009-0006-3611-0115
Collin ShannonMechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Junlin ChenMechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.
Piyush ShethK Medical LLC, Porter Ranch, CA 91326, USA.
Jonathan B HopkinsMechanical and Aerospace Engineering, University of California, Los Angeles, Los Angeles, CA 90095, USA.ORCID 0000-0003-4752-746X

Funding

Multi-Stable Compliant-Mechanism-Based Mattress for Bedsore PreventionR44NR019721 · NINR · K MEDICAL LLC · PI DICIANNO, BRAD E., HOPKINS, JONATHAN · 2022 to 2023
$1.8M
Multi-stable Compliant-Mechanism-based Mattress for Bedsore PreventionR41NR019721 · NINR · K MEDICAL LLC · PI HOPKINS, JONATHAN · 2021 to 2021
$251k
NINR NIH HHS R41 NR019721NINR NIH HHS R44 NR019721
6 · The paper itself

Abstract

Despite the devastating effects of pressure ulcers (PUs), little is understood about how they can be prevented using alternating-pressure (AP) mattresses. Such mattresses typically aim to minimize the pressures imparted while alternating between different states of pressure to prevent areas of tissue from being persistently occluded of blood flow. In this work, we built an actuator bed to study AP approaches and learned that AP mattresses should aim to increase-not decrease-peak pressures to a certain extent if such areas are to be minimized for effectively preventing PUs. In addition, we learned that such mattresses should aim to increase the difference between their loading and off-loading pressures. We identified optimal parameters from the study and used them to design an AP mattress made of compliant mechanisms that markedly reduce areas of persistent occlusion by exhibiting relatively high peak pressures that are periodically alternated with substantially lower off-loading pressures. The mattress's performance was characterized and compared against a standard foam pad in its flat and raised configurations. The load required to actuate the mattress from one of its stable states of pressure to the other was also measured.

Indexed as

BedsPressure UlcerRoboticsEquipment DesignHumansPressure

Identifiers

PMID40531960
PMCPMC13384531

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.