Evidence map›Paper›PMID 40531888›Full record

ArticlePloS one2025

Accuracy of bedside ultrasound for predicting resting energy expenditure in critically ill patients: A feasibility study.

Ming Gao, Li Tan, Yingli Zhou, Wei Peng, Yuan Xu, Hua Zhou, Arthur Raymond Huber van Zanten, Yan Zhu

Abstract read
In one paragraph

Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ming GaoDepartment of Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Li TanDepartment of Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Yingli ZhouDepartment of Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Wei PengDepartment of Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Yuan XuDepartment of Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Hua ZhouDepartment of Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.
Arthur Raymond Huber van ZantenDepartment of Intensive Care Medicine, Gelderse Vallei Hospital, Ede, The Netherlands.
Yan ZhuDepartment of Critical Care Medicine, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua Medicine, Tsinghua University, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesThis study aimed to assess the accuracy of bedside ultrasound in predicting resting energy expenditure (REE) in critically ill patients.

methodsWe studied critically ill patients admitted to our hospital's ICU between November 2021 and March 2023 who underwent REE, cardiac ultrasound, and muscle ultrasound evaluations. General demographic information and ultrasound data (including cardiac output, biceps brachii and quadriceps femoris thickness) were collected to estimate REE (REE-US). Simultaneously, REE was measured using indirect calorimetry (REE-IC). Correlations between REE-US and established equations (Harris-Benedict, Penn State University (PSU), Mifflin, ASPEN standard) as well as REE-IC were evaluated. Additionally, the feasibility and application of ultrasound for REE prediction across different disease conditions in critically ill patients were analysed.

resultsNinety-seven critically ill patients with 124 ultrasound measurements were included. The Penn State University formula showed the highest correlation with REE-IC (r = 0.779, p < 0.001), followed by ultrasound estimation (r = 0.668, p < 0.001). Correlation between the PSU formula and REE-IC remained robust across subgroups. However, REE-US correlation was weaker in patients with low BMI (BMI < 20 kg/m2) (r = 0.521, p = 0.009) but comparable to the PSU formula in normal and high BMI groups (BMI 20-30 kg/m2: r = 0.682 vs. r = 0.714, p = 0.5743; BMI > 30 kg/m2: r = 0.712 vs. r = 0.882, p = 0.1294). In subgroup analysis, REE-US performed similarly to the PSU formula in the sepsis subgroup (r = 0.612 vs r = 0.661, p = 0.6852) and ICU patients in the late period of the acute phase (r = 0.675 vs r = 0.751, p = 0.2762).

conclusionsThe Penn State University formula demonstrated the strongest correlation with REE-IC in critically ill patients. Ultrasound may replace the PSU formula in non-mechanically ventilated patients with unavailable gas measurement parameters. However, ultrasound-derived REE is less predictive in patients with low BMI or during the early acute phase of critical illness. Further research is warranted to refine ultrasound application in these populations.

Indexed as

Critical IllnessEnergy MetabolismAdultAgedCalorimetry, IndirectFeasibility StudiesFemaleHumansIntensive Care UnitsMaleMiddle AgedPoint-of-Care SystemsUltrasonography

Identifiers

PMID40531888
PMCPMC12176121

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.