ArticleRevista da Associacao Medica Brasileira (1992)2025
Increased cervical disc degeneration in ischemic stroke: a 10-year retrospective data review.
Article in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to evaluate the relationship between cervical spine degeneration and stroke-related parameters in patients with ischemic stroke.
methodsThe records of the patients with ischemic stroke who had undergone cervical magnetic resonance imaging between October 2013 and 2023 were extracted retrospectively and assessed for eligibility. Age- and sex-matched controls were included for comparative analysis. Disease characteristics (side of stroke, localization, stroke volume, National Institutes of Health Stroke Scale, and affected circulation), presence of cardiac pathology and vascular risk factors, degree of carotid artery stenosis, and inflammatory markers of the patient group were recorded. Computerized measurements and evaluation of some study variables, including Pfirrmann classification, Modic changes, intervertebral disc protrusion, and intervertebral disc height, using magnetic resonance imaging scan were performed for all participants.
resultsA total of 290 patients with ischemic stroke who had undergone cervical magnetic resonance imaging examination were evaluated for eligibility. After applying the exclusion criteria, 45 patients remained (patient group). The median National Institutes of Health Stroke Scale score and stroke volume of the patients were 4 (3) and 1.07 (7.11) mm3, respectively. The Pfirrmann classification also differed between groups (p<0.001). Modic degeneration distribution did not differ between the study groups.
conclusionThe current study confirmed that patients with acute ischemic stroke revealed higher disc degeneration and increased disc protrusion in the cervical spine. Similar underlying mechanisms in stroke and cervical disc degeneration may play a role in these results. This point should be further studied in order to come up with a clear conclusion.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.