Trial reportRevista da Associacao Medica Brasileira (1992)2025
Carbetocin versus oxytocin in the management of the third stage of labor for preventing postpartum hemorrhage after vaginal delivery.
Trial report in Revista da Associacao Medica Brasileira (1992), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The effects of oxytocin and carbetocin on hemostatic parameters in women after spontaneous vaginal delivery: a randomized trial.Revista da Associacao Medica Brasileira (1992) · 2026Trial
Corrections and comments
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Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThe aim of this study was to compare the effect of carbetocin and oxytocin administration on the prevention of postpartum hemorrhage concerning the estimated amount of bleeding, the need for additional uterotonics, and alterations in hemoglobin levels in patients undergoing vaginal delivery.
methodsA cohort investigation was carried out at a tertiary hospital from November 2020 to December 2023, comprising women who underwent vaginal delivery and exhibited at least one risk factor for atonic postpartum hemorrhage. The study included pregnant women at gestational ages between 37 and 40 weeks. Following vaginal delivery, the participants were randomly assigned to receive either five units of oxytocin or 100 μg of carbetocin intravenously. Postpartum blood loss was subsequently measured objectively in milliliters using a calibrated bag attached to a postpartum drape.
resultsThe peripartum estimated bleeding volumes for the oxytocin and carbetocin groups were 461.41±65.41 cc and 446.35±68.18 cc, respectively (p=0.096). There was no statistically significant difference observed between the two groups in terms of hemoglobin decrease and additional uterotonic requirement (p=0.904 and p=0.348, respectively).
conclusionThe findings suggest that carbetocin was equally effective and safe compared to oxytocin in preventing postpartum hemorrhage among women undergoing vaginal delivery.
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