Evidence map›Paper›PMID 40531752›Full record

ArticleBrazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica2025

Microencapsulation of fish oil by spray-drying using two different wall materials: a comparison.

S C B Pinto, A M Kluczkovski, H B Lemos, V G Torres, A V B Jesus, T P Souza

Abstract readComparative Study
In one paragraph

Article in Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

S C B PintoFaculdade de Ciências Farmacêuticas, Universidade Federal do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0001-6055-1347
A M KluczkovskiFaculdade de Ciências Farmacêuticas, Universidade Federal do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0009-0006-3586-8039
H B LemosFaculdade de Ciências Farmacêuticas, Universidade Federal do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0009-0005-0108-8010
V G TorresFaculdade de Ciências Farmacêuticas, Universidade Federal do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0009-0007-9645-3897
A V B JesusFaculdade de Ciências Farmacêuticas, Universidade Federal do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0009-0009-7781-1446
T P SouzaFaculdade de Ciências Farmacêuticas, Universidade Federal do Amazonas, Manaus, AM, Brasil.ORCID http://orcid.org/0000-0003-1164-2191

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Oils and fats have a wide range of health benefits, especially those that have a high concentration of polyunsaturated fatty acids, like fish oils. Unfortunately, oils are highly susceptible to heat, light, and oxygen degradation, causing them to lose the qualities that would make them interesting for the public. With this in mind, this study compared two methods of spray-drying, a technique that helps preserve the stability of oils in storage for longer periods of time. Emulsions made with skimmed milk powder and with maltodextrin and whey protein hydrolysate were spray-dried, resulting in 2 different microencapsulated fish oils. They were compared regarding encapsulation efficiency, water activity, moisture content, and peroxide index. The skimmed milk showed better results, with a 28.17% lower peroxide index than the non-encapsulated oil and lower water activity and moisture content compared to the emulsion using maltodextrin (2.690±0.19% vs 6.747±0.29% moisture content and 0.376±0.013 vs 0.554±0.006 water activity). Since skimmed milk powder is rather cheap, it is ideal for spray-drying, a simple and fast technique. In this way, fish oil can be safely microencapsulated in powder form, lasting longer than the oil capsules currently available, since the oil is protected from light, temperature, moisture, and oxidation. In addition, the oily odor is masked, making it more appealing to the consumer, and it may be combined with other powders, like vitamins and minerals, which opens up new possibilities for the production of supplements.

Indexed as

DesiccationDrug CompoundingFish OilsMilkPolysaccharidesSpray DryingAnimalsDrug StabilityEmulsionsPowdersWhey ProteinsEmulsionsFish OilsmaltodextrinPolysaccharidesPowdersWhey Proteins

Identifiers

PMID40531752
PMCPMC12172157

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.