Evidence map›Paper›PMID 40531373›Full record

SynthesisSpine deformity2025

Incidence of neurological deficits following proximal junctional kyphosis or failure in adult spinal deformity surgery: a systematic review and meta-analysis.

Abdullah M Alharran, Muteb N Alotaibi, Nizar Algarni, Mohammad A M A Mohammad, Mohammed T M H Alajmi, Ahmad A Alahmad, Yousef Marwan

Abstract readSystematic ReviewMeta-Analysis
PubMed Publisher
In one paragraph

Synthesis in Spine deformity, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Abdullah M AlharranCollege of Medicine, Arabian Gulf University, Manama, Kingdom of Bahrain. Abdullahah@agu.edu.bh.ORCID http://orcid.org/0009-0003-2337-6588
Muteb N AlotaibiCollege of Medicine, AL Faisal University, Riyadh, Saudi Arabia.
Nizar AlgarniDepartment of Orthopaedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Mohammad A M A MohammadCollege of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Mohammed T M H AlajmiCollege of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Ahmad A AlahmadCollege of Medicine, Royal College of Surgeons in Ireland, Dublin, Ireland.
Yousef MarwanDepartment of Surgery, College of Medicine, Health Sciences Center, Kuwait University, Kuwait City, Kuwait.ORCID http://orcid.org/0000-0001-5450-523X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAdult spinal deformity surgery is frequently performed to address degenerative conditions and scoliosis, but postoperative complications such as proximal junctional kyphosis (PJK) and proximal junctional failure (PJF) are common. These conditions can lead to neurological deficits and compromised surgical outcomes. This systematic review and meta-analysis aimed to evaluate the prevalence of neurological deficits associated with PJK and PJF.

methodsA systematic review and meta-analysis was conducted following PRISMA guidelines. A comprehensive search was performed across multiple databases, including PubMed, Web of Science, Cochrane, Embase, and Scopus, with no language restrictions. Studies that reported neurological deficits following PJK or PJF after adult spinal deformity surgery were included. Data extraction and quality assessment were performed by two independent authors using NIH quality assessment tools. Meta-analysis was conducted using random-effect models, and heterogeneity was evaluated using I

resultsThirteen eligible studies were identified involving 2846 patients. Of these, 777 patients developed PJK or PJF, with 61 patients experiencing neurological deficits. The pooled prevalence of neurological deficits was 6.2% for PJF (95% CI: 0.062-0.192; p < 0.001) and 7.1% for PJK (95% CI: 0.027-0.115; p < 0.001). Heterogeneity amongst the studies was high for PJF (I

conclusionThis study highlights the incidence of neurological deficits following PJK and PJF in adult spinal deformity surgeries. Future research should focus on identifying the risk factors and utilising evidence-based strategies that can improve postoperative care and reduce complication rates.

Indexed as

KyphosisNervous System DiseasesPostoperative ComplicationsScoliosisSpinal FusionAdultHumansIncidencePrevalenceTreatment FailureNeurological deficitsProximal junctional failureProximal junctional kyphosisSpinal deformity surgerySystematic review

Identifiers

PMID40531373

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.