Evidence map›Paper›PMID 40531347›Full record

Trial reportJournal of applied physiology (Bethesda, Md. : 1985)2025

Evaluating low-energy cooling strategies on thermal and cardiac strain in older adults exposed to very hot and dry heat with accompanying activities of daily living.

Zachary J McKenna, Whitley C Atkins, Satyam Sarma, Elizabeth A Gideon, Taysom Wallace, Isa A Farooqi, Zachary R Oldham, Craig G Crandall

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in Journal of applied physiology (Bethesda, Md. : 1985), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Trial
  2. Older adults and extreme weather events: recommendations from the Research Centers Collaborative Network workshop.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026
    Article
  3. The physiology of survival: Heat.Experimental physiology · 2026
    Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Zachary J McKennaInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0003-2502-8870
Whitley C AtkinsInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.
Satyam SarmaInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.
Elizabeth A GideonInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0009-0002-6877-681X
Taysom WallaceInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0009-0004-6002-778X
Isa A FarooqiInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.
Zachary R OldhamInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0009-0001-6456-4441
Craig G CrandallInstitute for Exercise and Environmental Medicine, Texas Health Presbyterian Hospital Dallas, Dallas, Texas, United States.ORCID 0000-0001-7792-9713

Funding

Heat waves and the elderly: reducing thermal and cardiovascular consequencesR01AG069005 · NIA · UT SOUTHWESTERN MEDICAL CENTER · PI CRANDALL, CRAIG G · 2021 to 2025
$2.8M
Low-energy cooling strategies to reduce the thermal, cardiovascular, and renal consequences of heat waves in the elderly.F32HL168826 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI MCKENNA, ZACHARY JOHN · 2024 to 2025
$149k
American Heart Association (AHA) 23POST1023065American Heart Association (AHA) 24POST1192222American Heart Association-American Stroke Association 23POST1023065HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) F32HL168826HHS | NIH | National Institute on Aging (NIA) R01AG069005NHLBI NIH HHS F32 HL168826NIA NIH HHS R01 AG069005
6 · The paper itself

Abstract

We tested the hypothesis that skin wetting would attenuate, whereas electric fans would increase, thermal and cardiac strain in older adults exposed to very hot and dry heat. Twenty-three older adults (66-84 yr) were exposed (randomized) to 3 h of ambient heating (47°C and 15% relative humidity) with water spray, fan use, water spray + fan use, or no cooling intervention. We assessed thermal, cardiovascular, and cardiac responses. Compared with control, water spray reduced the increase in core temperature by -0.24°C [95% CI: -0.42, -0.06] (

Indexed as

Activities of Daily LivingBody Temperature RegulationHeartHot TemperatureAgedAged, 80 and overBody TemperatureFemaleHeart RateHumansHumidityMaleSkin TemperatureSweatingagingcardiacheat stresshyperthermia

Identifiers

PMID40531347
PMCPMC12256998

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.