Evidence map›Paper›PMID 40531308›Full record

ReviewGraefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie2025

Connecting the dots: the role of genetics in posterior vitreous detachment.

Rajya L Gurung, Stewart Lake, Shane Durkin, David Sia, Jagjit Gilhotra, Weng Onn Chan

Abstract readReview
PubMed Publisher
In one paragraph

Review in Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rajya L GurungDepartment of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia. rajya.gurung@sa.gov.au.ORCID http://orcid.org/0000-0003-0816-9823
Stewart LakeDepartment of Ophthalmology, Flinders Medical Centre, Adelaide, South Australia, Australia.
Shane DurkinDepartment of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
David SiaDepartment of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Jagjit GilhotraDepartment of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.
Weng Onn ChanDepartment of Ophthalmology, Royal Adelaide Hospital, Adelaide, South Australia, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The vitreous is a transparent homogenous gel comprised predominantly of water. It is firmly attached to the internal limiting membrane in young healthy individuals. As part of the physiological aging process, the separation of the posterior vitreous cortex from the internal limiting membrane is called physiological posterior vitreous detachment (PVD), which usually occurs without ocular complications. On the contrary, anomalous PVD can have various sight-threatening complications. The cause of this difference is poorly understood and is a topic of future research. Further, newer evidence indicates that anomalous PVD may be genetically influenced.

Indexed as

Vitreous BodyVitreous DetachmentHumansAnomalous posterior vitreous detachmentGeneticsPathogenesisVitreous

Identifiers

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.