Evidence map›Paper›PMID 40531262›Full record

SynthesisDigestive diseases and sciences2025

An Audit of Indications for Endoscopic Submucosal Dissection for Colorectal Lesions in North America: A Systematic Review and Meta-Analysis.

Taylor Bowler, Erica Loon, Sahib Singh, Himsikhar Khataniar, Iman Afraz, Muhammad Ali Butt, Azizullah Beran, Nicole Theis-Mahon, Natalie Wilson, Rahul Karna and 1 more

Abstract readMeta-AnalysisSystematic Review
PubMed Publisher
In one paragraph

Synthesis in Digestive diseases and sciences, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Taylor BowlerDepartment of Internal Medicine, University of Minnesota Medical Center, Minneapolis, MN, USA.
Erica LoonDepartment of Internal Medicine, University of Minnesota Medical Center, Minneapolis, MN, USA.
Sahib SinghDepartment of Internal Medicine, Sinai Hospital, Baltimore, MD, USA.
Himsikhar KhataniarDepartment of Internal Medicine, Allegheny General Hospital, Pittsburgh, PA, USA.
Iman AfrazIslamabad Medical and Dental College, Islamabad, Pakistan.
Muhammad Ali ButtDepartment of Internal Medicine, Allegheny General Hospital, Pittsburgh, PA, USA.
Azizullah BeranDepartment of Gastroenterology and Hepatology, Indiana University School of Medicine, Indianapolis, IN, USA.
Nicole Theis-MahonDepartment of Internal Medicine, University of Minnesota Medical Center, Minneapolis, MN, USA.
Natalie WilsonDepartment of Internal Medicine, University of Minnesota Medical Center, Minneapolis, MN, USA.
Rahul KarnaDepartment of Gastroenterology, Hepatology and Nutrition, University of Minnesota Medical Center, Minneapolis, MN, USA.
Mohammad BilalDivision of Gastroenterology and Hepatology, University of Colorado Anschutz Medical Campus, 13001 E 17th Place, Aurora, CO, 80045, USA. bilal17@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Endoscopic mucosal resection (EMR) is a safe and effective treatment for most large colorectal lesions Endoscopic submucosal dissection (ESD) can be performed in cases suspicious for superficial submucosal invas. This decision is often operator dependent and based on optical diagnosis of polyp morphology and surface vascular and pit pattern. Here, we conduct a systematic review and meta-analysis of ESD performed for colorectal lesions in North America to evaluate the proportion of ESD performed for benign colorectal lesions. A comprehensive literature search of multiple electronic databases was conducted to identify all studies assessing ESD for colorectal lesions in North America. The primary outcome was pooled proportion of ESD performed for benign colorectal lesions based on histopathology. Secondary outcomes included procedure-related outcomes and adverse events of ESD. Pooled proportion of ESD for benign lesions was 83.81% (95% CI: 78.8-88.2; I

Indexed as

AdenomaColonoscopyColorectal NeoplasmsEndoscopic Mucosal ResectionHumansNorth AmericaBenign colorectal lesionsEndoscopic resectionEndoscopic submucosal dissectionLarge non-pedunculated colorectal polyps

Identifiers

PMID40531262

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.