Observational studyJapanese journal of ophthalmology2025
Choroidal changes after vitrectomy performed for macular hole retinal detachment.
Observational study in Japanese journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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Who cites it
1 citing paper in PubMed.
- Perfluorocarbon liquid-assisted inverted multilayer internal limiting membrane flaps covering for macular hole retinal detachment in high myopia with axial length ≥30 mm.International journal of ophthalmology · 2025Article
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Authors and funding
3 authors.
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Abstract
purposeTo investigate changes in the choroidal area (CA), luminal area (LA), stromal area (SA), choroidal vascularity index (CVI), and choroidal thickness (CT) before and after vitrectomy in eyes with macular hole retinal detachment (MHRD). STUDY
designRetrospective observational study.
methodsWe measured the best-corrected visual acuity (BCVA), intraocular pressure (IOP), CA, LA, SA, CVI, and CT preoperatively and 1, 3, and 6 months postoperatively in 10 eyes with MHRD. CA was measured within a 3-mm-wide area around the fovea in the horizontal and vertical images. LA and SA were quantified using the Niblack method, and CVI was calculated as the ratio of LA to CA. CT was measured at the subfovea and at 1 and 3 mm vertically and horizontally away from the fovea.
resultsBCVA improved significantly at 1 and 3 months postoperatively (P = 0.036 and 0.016). IOP remained stable. CA and LA decreased significantly 6 months postoperatively in both the horizontal (P = 0.002 and 0.014) and vertical sections (P = 0.006 and 0.002). SA remained stable. CVI reduced significantly at 1 month horizontally and at 3 months vertically (both P = 0.027). CT decreased significantly in the subfovea at 3 and 6 months postoperatively (P = 0.027 and 0.020, respectively). Significant reductions were also observed at 1 mm nasal, temporal, and superior regions (P = 0.014, 0.014, and 0.004) and at 2 mm temporal and superior regions 1 month postoperatively (P = 0.020 and 0.014).
conclusionChoroidal thinning was observed after vitrectomy in eyes with MHRD, driven by a reduction in the luminal area.
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