Evidence map›Paper›PMID 40531207›Full record

ReviewDie Anaesthesiologie2025

[Special aspects of patients with va-ECMO on the way to organ donation].

Esther Tautz, Johann Lambeck, Klaus Michael Lücking, Dominik Bettinger, Michael Zinner, Alexander Supady, Guido Michels, Dawid L Staudacher

Abstract readEnglish AbstractReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Die Anaesthesiologie, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Esther TautzInterdisziplinäre Medizinische Intensivtherapie (IMIT), Universitätsklinikum Freiburg, Medizinische Fakultät, Universität Freiburg, Hugstetter Str. 55, 79106, Freiburg, Deutschland. esther.tautz@uniklinik-freiburg.de.
Johann LambeckKlinik für Neurologie und Neurophysiologie, Universitätsklinikum Freiburg, Breisacherstr. 64, 79106, Freiburg, Deutschland.
Klaus Michael LückingStabsstelle Organspende, Universitätsklinikum Freiburg, Freiburg im Breisgau, Deutschland.
Dominik BettingerKlinik für Innere Medizin II, Universitätsklinikum Freiburg, Medizinische Fakultät, Albert-Ludwigs-Universität Freiburg, Hugstetter Str. 55, D-79106 Freiburg, Deutschland.
Michael ZinnerInterdisziplinäre Medizinische Intensivtherapie (IMIT), Universitätsklinikum Freiburg, Medizinische Fakultät, Universität Freiburg, Hugstetter Str. 55, 79106, Freiburg, Deutschland.
Alexander SupadyInterdisziplinäre Medizinische Intensivtherapie (IMIT), Universitätsklinikum Freiburg, Medizinische Fakultät, Universität Freiburg, Hugstetter Str. 55, 79106, Freiburg, Deutschland.
Guido MichelsNotfallzentrum, Krankenhaus der Barmherzigen Brüder Trier, Medizincampus Trier der Universitätsmedizin Mainz, Trier, Deutschland.
Dawid L StaudacherInterdisziplinäre Medizinische Intensivtherapie (IMIT), Universitätsklinikum Freiburg, Medizinische Fakultät, Universität Freiburg, Hugstetter Str. 55, 79106, Freiburg, Deutschland.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The treatment of potential organ donors on veno-arterial extracorporeal membrane oxygenation (va-ECMO) is complex and resource-intensive due to the challenges of ECMO support itself and due to the severity of the underlying disease, typically associated with profound shock. This shock can lead to multiorgan failure, which can negatively impact the suitability of potential organs for transplantation; however, ECMO offers a chance for recovery of acutely impaired organs, as adequate perfusion is provided. In addition, profound pathophysiological changes can occur in the context of brain death/death by neurologic criteria (BD/DNC) which, in particular, can cause cardiorespiratory, immunological and endocrinological disorders. Specific knowledge is required concerning the diagnosis of BD/DNC as well as cardiorespiratory, gastroenterological, nephrological and coagulation-related aspects. Particularly in view of the shortage of donor organs, this group of patients should not be denied the wish for organ donation if BD/DNC occurs in the context of severe brain injury under ongoing ECMO support. The aim of this review article is to provide an overview of special aspects in the care of potential organ donors on ECMO.

Indexed as

Extracorporeal Membrane OxygenationTissue and Organ ProcurementTissue DonorsBrain DeathHumansMultiple Organ FailureBrain death/death by neurologic criteriaDonor managementIntensive careMultiorgan failureVeno-arterial extracorporeal membrane oxygenation

Identifiers

PMID40531207
PMCPMC12222430

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.