ArticleBrazilian journal of cardiovascular surgery2025
Effect of Systemic Immune-Inflammation Index on Prognosis in Non-Functional Mitral Regurgitation Patients Undergoing Isolated Mitral Valve Replacement.
Article in Brazilian journal of cardiovascular surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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1 citing paper in PubMed.
- Inflammatory index-based nomogram for risk stratification of erectile dysfunction: a cross-sectional study with dual-cohort validation and mendelian randomization analysis.Translational andrology and urology · 2025Article
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5 authors.
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Abstract
objectiveTo investigate the effect of preoperative and postoperative systemic immune-inflammation index (SII) values on early prognosis in patients with nonfunctional mitral regurgitation etiology undergoing isolated mitral valve replacement (MVR).
methodsA total of 176 patients with isolated MVR performed from 2015 to 2021 were retrospectively investigated. The platelet, lymphocyte, and neutrophil counts were measured, and SII, neutrophil/lymphocyte ratio (NLR), and platelet/lymphocyte ratio (PLR) values were calculated preoperatively and on the first and fourth days postoperatively. The correlations with postoperative 30-day early-term prognosis and mortality were investigated.
resultsMean age of the patients was 55.4 years, 69.9% were female, and 30.1% were male. At 30-day follow-up, 9% (n = 16) of patients died. There were significant positive correlations observed between age (P < 0.001), preoperative NLR (P = 0.003), preoperative SII (P = 0.02), and postoperative fourth day NLR (P < 0.001) values with 30-day mortality. Receiver operating characteristic analysis identified that age + preoperative SII (P < 0.001), age + preoperative NLR (P < 0.001), and age + postoperative fourth day NLR (P = 0.001) combinations were significant predictive factors for 30-day mortality. There was a significant positive correlation between postoperative fourth day SII value with intensive care unit (ICU) admission duration (P < 0.001, Ρ = 0.308).
conclusionFor non-functional, isolated MVR patients, preoperative and postoperative fourth day SII and NLR values were found to provide an idea about 30-day prognosis. Additionally, patients with high postoperative fourth day SII values were observed to have longer ICU stays.
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