Evidence map›Paper›PMID 40530983›Full record

Observational studyAmerican journal of respiratory and critical care medicine2025

Performance Characteristics for Physiological Measures of Progressive Pulmonary Fibrosis.

Chad A Newton, Ashwatha Thenappan, Gabrielle Y Liu, Leda Yazbeck, Cathryn T Lee, Janelle Vu Pugashetti, Jennifer M Wang, Ethan White, Kevin R Flaherty, Elizabeth A Belloli and 21 more

Abstract readMulticenter StudyObservational Study
In one paragraph

Observational study in American journal of respiratory and critical care medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Observational
  3. Article
  4. A multidimensional index with SpORespiratory research & clinical practice · 2026
    Article
  5. Article
  6. Progress in Progressive Pulmonary Fibrosis.American journal of respiratory and critical care medicine · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

31 authors.

Chad A NewtonDivision of Pulmonary and Critical Care Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.ORCID 0000-0001-5256-9029
Ashwatha ThenappanDepartment of Internal Medicine.
Gabrielle Y LiuDivision of Pulmonary, Critical Care and Sleep Medicine, University of California, Davis, Davis, California.
Leda YazbeckNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Cathryn T LeeSection of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois.
Janelle Vu PugashettiDivision of Pulmonary and Critical Care Medicine, and.ORCID 0000-0002-8889-2757
Jennifer M WangDivision of Pulmonary and Critical Care Medicine, and.ORCID 0000-0003-4670-7549
Ethan WhiteDivision of Pulmonary and Critical Care Medicine, and.
Kevin R FlahertyDivision of Pulmonary and Critical Care Medicine, and.
Elizabeth A BelloliDivision of Pulmonary and Critical Care Medicine, and.
Jamie S ShethDivision of Pulmonary and Critical Care Medicine, and.
Nisha MohanDivision of Pulmonary and Critical Care Medicine, and.
Nazanin NazemiDivision of Pulmonary and Critical Care Medicine, and.
Andrew R YuDivision of Pulmonary and Critical Care Medicine, University of Texas Southwestern Medical Center, Dallas, Texas.
Sahand GhodratiDivision of Pulmonary, Critical Care and Sleep Medicine, University of California, Davis, Davis, California.
Kerri A JohannsonDepartment of Medicine, University of Calgary, Calgary, Alberta, Canada.
Veronica MarcouxDepartment of Medicine, University of Saskatchewan, Saskatoon, Saskatchewan, Canada.ORCID 0000-0001-5890-3227
Jolene H FisherDepartment of Medicine, University of Toronto, Toronto, Ontario, Canada.
Deborah AssayagDepartment of Medicine, McGill University, Montreal, Quebec, Canada.ORCID 0000-0002-2497-9984
Helene ManganasDépartement de Médecine, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Nasreen KhalilDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Martin KolbDepartment of Medicine, Firestone Institute for Respiratory Health, McMaster University, Hamilton, Ontario, Canada.ORCID 0000-0003-3837-1467
Julie MorissetDépartement de Médecine, Centre Hospitalier de l'Université de Montréal, Montreal, Quebec, Canada.
Christine Kim GarciaDivision of Pulmonary and Critical Care Medicine, Columbia University, New York, New York.ORCID 0000-0002-0771-1249
Felix ChuaNational Heart and Lung Institute, Imperial College London, London, United Kingdom.
Mary E StrekSection of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois.
Yet H KhorRespiratory Research@Alfred, School of Translational Medicine, Monash University, Melbourne, Victoria, Australia; and.ORCID 0000-0002-5434-9342
Ayodeji AdegunsoyeSection of Pulmonary and Critical Care Medicine, University of Chicago, Chicago, Illinois.
Christopher J RyersonDepartment of Medicine, University of British Columbia, Vancouver, British Columbia, Canada.
Philip L MolyneauxNational Heart and Lung Institute, Imperial College London, London, United Kingdom.ORCID 0000-0003-1301-8800
Justin M OldhamDivision of Pulmonary and Critical Care Medicine, and.ORCID 0000-0003-4957-8869

Funding

UT Southwestern Center for Translational Medicine (UL1/KL2/TL1)UL1TR001105 · NCATS · UT SOUTHWESTERN MEDICAL CENTER · PI TOTO, ROBERT DANIEL · 2013 to 2017
$24.5M
PULMONARY CELLULAR AND MOLECULAR BIOLOGY TRAININGT32HL007749 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Robert Pickett Dickson · 1993 to 2026
$19.9M
RESEARCH TRAINING IN RESPIRATORY BIOLOGYT32HL007605 · NHLBI · UNIVERSITY OF CHICAGO · PI Yun Fang, Gokhan M. Mutlu · 1985 to 2026
$18.1M
TRAINING IN COMPARATIVE LUNG BIOLOGY AND MEDICINET32HL007013 · NHLBI · UNIVERSITY OF CALIFORNIA DAVIS · PI Elena Goncharova, Nicholas J. KENYON · 1985 to 2026
$10.1M
Pulmonary Fibrosis and Telomerase DysfunctionR01HL093096 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI GARCIA, CHRISTINE KIM · 2009 to 2024
$6.9M
Proteomic Profiling of Idiopathic Pulmonary Fibrosis Progression TrajectoryR01HL169166 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin M Oldham · 2023 to 2026
$2.7M
Prognostic Biomarker Development in Progressive Fibrosing Interstitial Lung DiseaseR01HL166290 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Justin M Oldham · 2024 to 2026
$2.2M
Elucidating the Genomic Determinants of Outcomes in Idiopathic Pulmonary FibrosisK23HL138190 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI OLDHAM, JUSTIN M · 2017 to 2021
$914k
Molecular Markers of Idiopathic Pulmonary Fibrosis ProgressionK23HL148498 · NHLBI · UT SOUTHWESTERN MEDICAL CENTER · PI NEWTON, CHAD ALAN · 2020 to 2024
$891k
Improving Pulmonary Fibrosis Classification with Genomics Informed Phenotypic ClustersK23HL146942 · NHLBI · UNIVERSITY OF CHICAGO · PI ADEGUNSOYE, AYODEJI · 2020 to 2024
$810k
Derivation and validation of a clinical-molecular signature to predict fibrotic progression and treatment response in patients with autoimmune interstitial lung diseaseR56HL158935 · NHLBI · UNIVERSITY OF CALIFORNIA AT DAVIS · PI OLDHAM, JUSTIN M · 2021 to 2021
$400k
A Multi-Dimensional Signature to Predict Treatment Failure in Patients with Connective Tissue Disease-Associated Interstitial Lung DiseaseK23HL171871 · NHLBI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Janelle Vu Pugashetti · 2025 to 2026
$392k
Asthma+Lung UKBoehringer IngelheimNCATS NIH HHS UL1 TR001105NCATS NIH HHS UL1TR001105NHLBI NIH HHS K23 HL138190NHLBI NIH HHS K23HL138190NHLBI NIH HHS K23 HL146942NHLBI NIH HHS K23HL146942NHLBI NIH HHS K23 HL148498NHLBI NIH HHS K23HL148498NHLBI NIH HHS K23 HL171871NHLBI NIH HHS L30 HL181822NHLBI NIH HHS R01 HL093096NHLBI NIH HHS R01HL093096NHLBI NIH HHS R01 HL166290NHLBI NIH HHS R01 HL169166NHLBI NIH HHS R56 HL158935NHLBI NIH HHS R56HL158935NHLBI NIH HHS T32 HL007013NHLBI NIH HHS T32HL007013NHLBI NIH HHS T32 HL007605NHLBI NIH HHS T32HL007605NHLBI NIH HHS T32 HL007749NHLBI NIH HHS T32HL007749
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Pulmonary FibrosisRespiratory Function TestsAgedCanadaDisease ProgressionFemaleHumansMaleMiddle AgedRetrospective StudiesROC CurveUnited KingdomUnited StatesVital Capacityidiopathic pulmonary fibrosisinterstitial lung diseaseprogressive fibrosing interstitial lung diseaseprogressive pulmonary fibrosistest performance characteristics

Identifiers

PMID40530983
PMCPMC12525792

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.