Evidence map›Paper›PMID 40530957›Full record

ArticleRadiology. Artificial intelligence2025

RadioRAG: Online Retrieval-Augmented Generation for Radiology Question Answering.

Soroosh Tayebi Arasteh, Mahshad Lotfinia, Keno Bressem, Robert Siepmann, Lisa Adams, Dyke Ferber, Christiane Kuhl, Jakob Nikolas Kather, Sven Nebelung, Daniel Truhn

Abstract read
In one paragraph

Article in Radiology. Artificial intelligence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed.

  1. Article
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  4. Review
  5. Article
  6. How to bring generative AI to oncology practice.ESMO real world data and digital oncology · 2026
    Review
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Soroosh Tayebi ArastehDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Germany.ORCID 0000-0003-1015-7733
Mahshad LotfiniaDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Germany.ORCID 0000-0001-7605-7992
Keno BressemInstitute for Radiology and Nuclear Medicine, German Heart Centre Munich, Technical University of Munich, Munich, Germany.ORCID 0000-0001-9249-8624
Robert SiepmannDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Germany.ORCID 0000-0002-4608-5180
Lisa AdamsDepartment of Radiology, Stanford University, Stanford, Calif.ORCID 0000-0001-5836-4542
Dyke FerberElse Kroener Fresenius Center for Digital Health, Faculty of Medicine, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.
Christiane KuhlDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Germany.ORCID 0000-0001-8696-2363
Jakob Nikolas KatherElse Kroener Fresenius Center for Digital Health, Faculty of Medicine, University Hospital Carl Gustav Carus, Dresden University of Technology, Dresden, Germany.ORCID 0000-0002-3730-5348
Sven NebelungDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Germany.ORCID 0000-0002-5267-9962
Daniel TruhnDepartment of Diagnostic and Interventional Radiology, University Hospital RWTH Aachen, Pauwelsstr 30, 52074 Aachen, Germany.ORCID 0000-0002-9605-0728

Funding

Integration of epidemiology, pathology, immunology and outcomes in colorectal cancerR01CA263318 · NCI · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI STEPHEN B GRUBER · 2022 to 2026
$3.4M
NCI NIH HHS R01 CA263318
6 · The paper itself

Abstract

Purpose To evaluate diagnostic accuracy of various large language models (LLMs) when answering radiology-specific questions with and without access to additional online, up-to-date information via retrieval-augmented generation (RAG). Materials and Methods The authors developed radiology RAG (RadioRAG), an end-to-end framework that retrieves data from authoritative radiologic online sources in real-time. RAG incorporates information retrieval from external sources to supplement the initial prompt, grounding the model's response in relevant information. Using 80 questions from the RSNA Case Collection across radiologic subspecialties and 24 additional expert-curated questions with reference standard answers, LLMs (GPT-3.5-turbo [OpenAI], GPT-4, Mistral 7B, Mixtral 8×7B [Mistral], and Llama3-8B and -70B [Meta]) were prompted with and without RadioRAG in a zero-shot inference scenario (temperature ≤ 0.1, top-p = 1). RadioRAG retrieved context-specific information from

Indexed as

Information Storage and RetrievalRadiologyHumansInternetComputer-aided DiagnosisInformaticsLarge Language ModelsRetrieval-augmented Generation

Identifiers

PMID40530957
PMCPMC12326075

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.