Evidence map›Paper›PMID 40530929›Full record

ReviewChemistry (Weinheim an der Bergstrasse, Germany)2025

Sustainable Approaches for the Protection and Deprotection of Functional Groups.

Ju Ha Jin, Mina An, Minki Jeon, Jaejeong Kim, Sung Min Kang, Isaac Choi

Abstract readReview
In one paragraph

Review in Chemistry (Weinheim an der Bergstrasse, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Design rules for externally triggered drug uncaging under optical and radiolytic regimes.European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V · 2026
    Review
  2. Article
  3. Deprotection of benzyl ethersGreen chemistry : an international journal and green chemistry resource : GC · 2026
    Article
  4. Electrooxidative Divergent Halocyclizations of Ambident Amides.Angewandte Chemie (International ed. in English) · 2026
    Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ju Ha JinDepartment of Chemistry, Chungbuk National University, Chungcheongbuk-do, 28644, Republic of Korea.
Mina AnDepartment of Chemistry, Chungbuk National University, Chungcheongbuk-do, 28644, Republic of Korea.
Minki JeonDepartment of Chemistry, Chungbuk National University, Chungcheongbuk-do, 28644, Republic of Korea.
Jaejeong KimDepartment of Chemistry, Chungbuk National University, Chungcheongbuk-do, 28644, Republic of Korea.
Sung Min KangDepartment of Chemistry, Chungbuk National University, Chungcheongbuk-do, 28644, Republic of Korea.
Isaac ChoiDepartment of Chemistry, Chungbuk National University, Chungcheongbuk-do, 28644, Republic of Korea.ORCID https://orcid.org/0000-0002-9207-4845

Funding

BK21 Program at Chungbuk National University (2023)National Research Foundation RS-2023-00210101National Research Foundation RS-2024-00445180
6 · The paper itself

Abstract

While functional group tolerance is a critical consideration in synthetic method development, many functional groups often fail to remain intact under diverse reaction conditions. Therefore, the protection of specific functional groups and subsequent deprotection are convenient choices for the efficient and selective synthesis of target compounds, for which the strategies have been securely established. Meanwhile, the development of sustainable synthetic methods, particularly electrochemistry and photochemistry, has recently played a significant role in the field of organic synthesis, and these approaches have proven useful in the methods of functional group protection and deprotection. This review explores electrochemical and photochemical strategies for the protection and deprotection of functional groups, with a focus on their mechanistic diversity, sustainability, and synthetic utility across various functional group classes.

Indexed as

electrochemistryfunctional group (de)protectionphotochemistryredox chemistrysustainable synthesis

Identifiers

PMID40530929
PMCPMC12272020

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.