Evidence map›Paper›PMID 40530876›Full record

ArticlemBio2025

Quorum sensing mediates morphology and motility transitions in the model archaeon

Priyanka Chatterjee, Caroline E Consoli, Heather Schiller, Kiersten K Winter, Monica E McCallum, Stefan Schulze, Mechthild Pohlschroder

Abstract read
In one paragraph

Article in mBio, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors.

Priyanka ChatterjeeDepartment of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-1608-7190
Caroline E ConsoliDepartment of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-8355-4644
Heather SchillerDepartment of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-7622-4735
Kiersten K WinterCollege of Science, Gosnell School of Life Sciences, Rochester Institute of Technology, Rochester, New York, USA.
Monica E McCallumDepartment of Chemistry, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-4549-4038
Stefan SchulzeDepartment of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-4771-7987
Mechthild PohlschroderDepartment of Biology, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-7729-1342

Funding

TRAINING PROGRAM IN CELL AND MOLECULAR BIOLOGYT32GM007229 · NIGMS · UNIVERSITY OF PENNSYLVANIA · PI BARTOLOMEI, MARISA S. · 1985 to 2023
$14.0M
Thermo Scientific Orbitrap Eclipse Tribrid ETD Mass Spectrometer for UConn ProteomicsS10OD028445 · OD · UNIVERSITY OF CONNECTICUT STORRS · PI BALSBAUGH, JEREMY · 2021 to 2021
$994k
Cell-cell signaling in archaea: How Haloferax volcanii talk to each otherF31AI181536 · NIAID · UNIVERSITY OF PENNSYLVANIA · PI CHATTERJEE, PRIYANKA · 2024 to 2025
$90k
National Science Foundation GRFPNational Science Foundation NSF-MBC2222076NIAID NIH HHS F31 AI181536NIGMS NIH HHS T32 GM007229NIH HHS 1F31AI181536-01NIH HHS S10 OD028445NIH HHS T32 GM007229RIT | College of Science, Rochester Institute of Technology (College of Science)University of Pennsylvania Research Fund Grant
6 · The paper itself

Abstract

Quorum sensing (QS) is a population density-dependent mechanism of intercellular communication, whereby microbes secrete and detect signals to regulate behaviors such as virulence and biofilm formation. Although QS is well-studied in bacteria, little is known about cell-cell communication in archaea. The model archaeon IMPORTANCE: Understanding the complex signaling networks in microbial communities has led to many invaluable applications in medicine and industry. Yet, while archaea are ubiquitous and play key roles in nutrient cycling, little is known about the roles of archaeal intra- and interspecies cell-cell communication in environments such as the human, soil, and marine microbiomes. In this study, we established the first robust system for studying quorum sensing in archaea by using the model archaeon

Indexed as

Haloferax volcaniiQuorum SensingArchaeal ProteinsCulture Media, ConditionedProteomeProteomicsArchaeal ProteinsCulture Media, ConditionedProteomearchaeacell shapeHaloferax volcaniiintercellular signalingmotilityquorum sensing

Identifiers

PMID40530876
PMCPMC12240190

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.