Evidence map›Paper›PMID 40530590›Full record

ArticleEarly intervention in psychiatry2025

Vocational Rehabilitation in Young Adults With Incident Schizophrenia-A Danish Retrospective Cohort Study.

Pernille Pedersen, Birthe Bruun Olsen, Ditte Lammers Vernal, Matilde Poulsen Rydborg, Christiane Gasse, Ole Mors

Abstract read
In one paragraph

Article in Early intervention in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Pernille PedersenDepartment of Public Health, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-2011-7877
Birthe Bruun OlsenDepartment of Psychosis, Aarhus University Hospital Psychiatry, Aarhus, Denmark.
Ditte Lammers VernalDepartment of Psychiatry, Aalborg University Hospital, Aalborg, Denmark.ORCID https://orcid.org/0000-0001-5096-2281
Matilde Poulsen RydborgDepartment of Psychiatry, Aalborg University Hospital, Aalborg, Denmark.ORCID https://orcid.org/0009-0004-0110-0895
Christiane GasseDepartment of Affective Disorders, Aarhus University Hospital Psychiatry, Aarhus, Denmark.ORCID https://orcid.org/0000-0001-6194-1099
Ole MorsDepartment of Clinical Medicine, Aarhus University, Aarhus, Denmark.ORCID https://orcid.org/0000-0002-5660-0393

Funding

Danish Regions EMN-2019-00852Health Research Foundation of Central Denmark Region A3280
6 · The paper itself

Abstract

introductionThe aim of this study was to compare the multidisciplinary vocational intervention, Morpheus, with standard vocational rehabilitation for young adults with incident schizophrenia undergoing the OPUS specialised early intervention programme. The study evaluated whether the type of vocational intervention was related to attachment to the labour market and educational system, outpatient contacts, hospital admissions and psychotropic drug use.

methodsThis retrospective cohort study included patients of the OPUS programme in the period from January 1, 2014, to December 31, 2019. Patients at Aarhus University Hospital Psychiatry (Aarhus) were offered the Morpheus intervention, while patients at Aalborg University Hospital (Aalborg) received standard vocational rehabilitation. The study used register and clinical data. The analyses involved logistic and linear regression presented as crude and adjusted models.

resultsOf the 404 OPUS patients from Aarhus and 246 OPUS patients from Aalborg, patients participating in the Morpheus intervention (n = 116) were more likely to be employed or enrolled in education 2 and 4 years after diagnosis compared with patients undergoing standard vocational intervention (n = 130). Specifically, the adjusted odds ratio for employment was 1.14 (0.37; 3.45) and 1.51 (0.70; 3.27) at 2 and 4 years, respectively. Morpheus patients were less likely to attend somatic outpatient contacts, which involve consultations or treatment for physical health conditions, as well as psychiatric outpatient contacts. Furthermore, they were less likely to be admitted to somatic departments or to redeem antipsychotic medication. However, Morpheus patients had a higher likelihood of being admitted to psychiatric departments during the periods 0-2 and 2-4 years after diagnosis.

conclusionYoung adults with incident schizophrenia receiving the Morpheus intervention within the OPUS treatment did not show statistically significant increased odds of employment or education enrolment compared to those in standard vocational rehabilitation.

Indexed as

Early Medical InterventionRehabilitation, VocationalSchizophreniaAdultDenmarkEmploymentFemaleHumansMaleRetrospective StudiesYoung Adulteducationmultidisciplinary collaborationschizophreniasupported employmentvocational rehabilitation

Identifiers

PMID40530590
PMCPMC12175208

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.