Evidence map›Paper›PMID 40530452›Full record

ArticleJournal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale

Outcomes Following Transoral Laser Microsurgery for T1b and T2a Glottic Squamous Cell Carcinoma With and Without Anterior Commissure Involvement: A Retrospective Chart Review.

Depak Patel, Victoria Taylor, Colin MacKay, Chrisje den Besten, Matthew H Rigby, Martin Corsten, Timothy Brown, Jonathan Trites, S Mark Taylor

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of otolaryngology - head & neck surgery = Le Journal d'oto-rhino-laryngologie et de chirurgie cervico-faciale. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Depak PatelDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, NS, Canada.ORCID 0000-0003-0892-1042
Victoria TaylorDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, NS, Canada.ORCID 0009-0000-5710-583X
Colin MacKayDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, NS, Canada.ORCID 0000-0002-5079-1862
Chrisje den BestenDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, NS, Canada.
Matthew H RigbyDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, NS, Canada.ORCID 0009-0008-2900-4626
Martin CorstenDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, NS, Canada.
Timothy BrownDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, NS, Canada.
Jonathan TritesDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, NS, Canada.
S Mark TaylorDivision of Otolaryngology-Head and Neck Surgery, Dalhousie University, Halifax, NS, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

ImportanceThere is a limited understanding of anterior commissure (AC) involvement in glottic squamous cell carcinoma (SCC), particularly when comparing T1b, T2a with AC involvement (T2AC), and T2a without AC involvement (T2noAC).ObjectiveThe aim of this study was to compare oncological and functional outcomes in T1b, T2AC, and T2noAC glottic SCC following transoral laser microsurgery (TLM).DesignRetrospective chart review.SettingThe Queen Elizabeth II Health Science Centre (Halifax, Nova Scotia) from January 1, 2002, to December 31, 2022.Intervention and ExposuresA retrospective chart review was completed using prospectively-collected data for patients treated with TLM for T1b and T2a glottic SCC. Exclusion criteria included previous treatment for a laryngeal cancer and T2b glottic SCC.Main Outcome MeasuresOncological outcomes were assessed using margin status, local control (LC), disease-specific survival (DSS), overall survival (OS), and laryngeal preservation (LP). Functional outcomes were measured using the abbreviated Voice Handicap Index-10 (VHI-10).ResultsIn total, 117 patients were included (T1b = 46, T2AC = 53, T2noAC = 18). Positive margins were higher in the T2AC group (15.1%) than in T1b (4.3%) and T2noAC (5.6%;

Indexed as

Carcinoma, Squamous CellGlottisLaryngeal NeoplasmsLaser TherapyMicrosurgeryAgedAged, 80 and overFemaleHumansMaleMiddle AgedNeoplasm StagingRetrospective StudiesTreatment Outcomeglottic cancerlaryngeal cancertransoral laser microsurgery

Identifiers

PMID40530452
PMCPMC12177246

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.