ArticleFrontiers in nephrology2025
Association between lactate dehydrogenase to albumin ratio and ICU mortality in patients with acute kidney injury: a retrospective cohort study.
Article in Frontiers in nephrology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Article
- Endothelial activation and stress index predicts 28-day mortality in patients undergoing CRRT.Biomolecules & biomedicine · 2025Article
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5 authors.
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Abstract
Background: Acute kidney injury (AKI) is a prevalent and severe medical condition that is frequently observed in the intensive care unit (ICU). Although numerous biomarkers have been identified to predict the prognosis of AKI, the lactate dehydrogenase to albumin ratio [LDH/ALB ratio (LAR)] has not been extensively investigated. The principal objective of this study was to assess the relationship between LAR and all-cause mortality in patients with AKI. Methods: A total of 6,831 AKI patients were included in this study, divided into survival (n = 5,152) and non-survival groups (n = 1,679). The association between LAR and mortality was examined through restricted cubic spline (RCS) analysis and Cox regression analysis. Subgroup analysis was used to search for interactive factors. Additionally, the prognostic capability of LAR was further evaluated using receiver operating characteristic (ROC) curve analysis. Results: The LAR was remarkably higher in the non-survival group ( Conclusion: Our research suggests that LAR monitoring may be promising as a prognostic marker among patients with AKI. Higher LAR is associated with greater ICU mortality.
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