Evidence map›Paper›PMID 40530336›Full record

ArticleFrontiers in cell and developmental biology2025

Establishment of human periodontal ligament cell lines with

Jana Schiffmaier, Sofia Rehling, Katharina Marnet, Angela Borst, Drenka Trivanović, Denitsa Docheva, Franz Jakob, Stephanie Graser, Marietta Herrmann, Daniel Liedtke

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in cell and developmental biology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Jana Schiffmaier *IZKF Group Tissue Regeneration in Musculoskeletal Diseases, University Hospital Würzburg, Würzburg, Germany.
Sofia Rehling *IZKF Group Tissue Regeneration in Musculoskeletal Diseases, University Hospital Würzburg, Würzburg, Germany.
Katharina MarnetIZKF Group Tissue Regeneration in Musculoskeletal Diseases, University Hospital Würzburg, Würzburg, Germany.
Angela BorstInstitute of Human Genetics, Biocenter, University of Würzburg, Würzburg, Germany.
Drenka TrivanovićIZKF Group Tissue Regeneration in Musculoskeletal Diseases, University Hospital Würzburg, Würzburg, Germany.
Denitsa DochevaDepartment of Musculoskeletal Tissue Regeneration, Bernhard-Heine-Center for Locomotion Research and Orthopedic Hospital König-Ludwig-Haus, University of Würzburg, Würzburg, Germany.
Franz JakobBernhard-Heine-Center for Locomotion Research, University of Würzburg, Würzburg, Germany.
Stephanie Graser *Bernhard-Heine-Center for Locomotion Research, University of Würzburg, Würzburg, Germany.
Marietta Herrmann *IZKF Group Tissue Regeneration in Musculoskeletal Diseases, University Hospital Würzburg, Würzburg, Germany.
Daniel Liedtke *Institute of Human Genetics, Biocenter, University of Würzburg, Würzburg, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Besides skeletal symptoms, dental abnormalities are a typical feature of the rare inherited disorder hypophosphatasia (HPP), which is caused by loss of function mutations in the Methods: We aimed to develop a physiologically relevant cellular model of dental origin with genetic Results: Detailed investigation of their genetic properties revealed that four different genotypes were successfully established at two different positions within the Discussion: We report the generation of a new set of immortalized

Indexed as

ALPLhypophosphatasiain vitroPDL-hTERT cellsTNAP

Identifiers

PMID40530336
PMCPMC12170583

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.