Evidence map›Paper›PMID 40530322›Full record

ArticleJournal of orthopaedics2025

A decade-long trends in ligamentum flavum hypertrophy among spinal stenosis patients: A comparative analysis of incidence and patterns.

Waleed Albishi, Mohammed N Alhuqbani, Omar A Aldosar, Zyad A Aldosari, Sara Alhomaidhi, Abdulrahman Alaseem, Waleed Awwad

Abstract read
In one paragraph

Article in Journal of orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Waleed AlbishiDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Mohammed N AlhuqbaniDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Omar A AldosarDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Zyad A AldosariDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Sara AlhomaidhiDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Abdulrahman AlaseemDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.
Waleed AwwadDepartment of Orthopedic Surgery, College of Medicine, King Saud University, Riyadh, Saudi Arabia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Lumbar spinal stenosis (LSS) is a prevalent degenerative condition, with ligamentum flavum hypertrophy (LFH) contributing significantly to neural compression. Despite its clinical importance, few studies have evaluated longitudinal trends in LFH. This study investigates the temporal progression and demographic associations of LFH over the past decade. Methods: This retrospective cohort study included adult patients undergoing surgery for LSS at a tertiary academic center during two periods: 2013-2017 and 2018-2023. Exclusion criteria included prior spinal surgery, trauma, malignancy, or inadequate imaging. Two radiologists reviewed axial MRI images to measure ligamentum flavum thickness (≥4 mm indicated hypertrophy). Demographic data and coexisting spinal conditions were also recorded. Results: A total of 202 patients were analyzed-98 from the initial and 104 from the later period. LFH prevalence rose from 24.5 % to 44.7 % over time. Patients aged ≥60 demonstrated significantly higher LFH rates in both periods (p = 0.004). Although female predominance persisted, it declined from 71.4 % to 55 %. LFH was most commonly associated with disc bulging, particularly at the same spinal level. Multilevel LFH increased from 25 % to 44.1 %, though L4-L5 remained the most affected segment. Conclusion: The incidence of LFH has increased substantially over the past decade, particularly among older adults. Given its role in LSS pathogenesis, greater attention to LFH in imaging and surgical planning is warranted. Further research is needed to clarify its etiology and guide effective management strategies.

Indexed as

Ligamentum flavumLumbar vertebraeSpinal stenosis

Identifiers

PMID40530322
PMCPMC12167823

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.