ArticleFrontiers in aging2025
Right hemisphere engagement in language abilities in older adults: indication of compensation rather than decline.
Article in Frontiers in aging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Association of Malaysian-MIND Diet Scores with Brain Activation in Older Adults: A Functional MRI Study.Biomedicines · 2026Article
- Computerized adaptation and validity evidence of the test of assessment of syntactic processing in comprehension (TASComp) in Brazilian adults.Frontiers in human neuroscience · 2026Article
- Beyond the left cerebral hemisphere: bilateral language lateralization in healthy aging and its clinical implications.Frontiers in aging neuroscience · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Introduction: Structural brain changes during aging have been used as specific markers to distinguish normal aging from dementia. Changes in specific cognitive abilities such as episodic memory, processing speed, and executive functions, are observed in healthy aging. Limited evidence reports changes in linguistic functions alongside structural and functional brain changes. This study investigates correlations between language performance, gray matter volume (GMV), and neural activity in language regions, adjusted for demographic factors, in healthy older adults. Methods: Twenty-seven right-handed participants aged 60-87 were evaluated for overall linguistic performance using the Spanish version of ScreeLing (SCL) test and phonemic fluency and semantic verbal fluency tasks (PF and SF). Participants also underwent an MRI session during which they performed a functional MRI language task. T1-weighted MRI scans were used to measure GMV in specific language-related regions and assess language lateralization. Correlational analyses were conducted between language scores, GMV, years of education, age, sex, and fMRI lateralization. Results: In the right hemisphere (RH), significant positive correlations were found between SCL scores and GMV in the orbital inferior frontal gyrus (r = 0.5402; p = 0.0044) and the superior temporal gyrus (r = 0.516; p = 0.007). Furthermore, SCL and Phonemic fluency positively correlated with years of education, indicating that higher education enhances speech performance. No significant correlations were found in the left hemisphere (LH). Age, sex, and fMRI lateralization did not significantly correlate with specific linguistic scores. Discussion: These results challenge the current view of the role of the right hemisphere in language performance as increased GMV in specific right hemisphere language regions is associated with better language performance, highlighting the role of the right hemisphere in supporting language skills during healthy aging.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.