Evidence map›Paper›PMID 40530114›Full record

ArticleTranslational cancer research2025

Development of a prognostic nomogram and risk factor analysis for survival in

Jing Wu, Xiancai Du, Wenwen Chen, Ting Ma, Lu Tian, Hong Zhang, Guanhua Wang, Wenjun Yang

Abstract read
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Article in Translational cancer research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Jing Wu *School of Basic Medical Science, Ningxia Medical University, Yinchuan, China.
Xiancai Du *School of Medicine, Southern University of Science and Technology, Shenzhen, China.
Wenwen Chen *School of Basic Medical Science, Ningxia Medical University, Yinchuan, China.
Ting MaSchool of Basic Medical Science, Ningxia Medical University, Yinchuan, China.
Lu TianSchool of Basic Medical Science, Ningxia Medical University, Yinchuan, China.
Hong ZhangSchool of Basic Medical Science, Ningxia Medical University, Yinchuan, China.
Guanhua WangSchool of Basic Medical Science, Ningxia Medical University, Yinchuan, China.
Wenjun YangSchool of Basic Medical Science, Ningxia Medical University, Yinchuan, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Currently, there is limited research on the prognosis and influencing factors of non-cardia gastric adenocarcinoma (NCGAC) patients. This study aims to explore the factors influencing overall survival (OS) in Methods: We retrospectively analyzed clinicopathological data from 413 Results: Univariate Cox regression analysis was performed on the training cohort to select variables with P<0.5, including alcohol consumption, tumor size, differentiation grade, lymph node metastasis, tumor (T) stage, node (N) stage, and tumor node metastasis (TNM) stage. Multicollinearity was assessed, and covariates with VIF >4, such as lymph node metastasis, were excluded. The remaining factors were included in the multivariate Cox regression model. Significant variables (P<0.05), including alcohol consumption, differentiation grade, and T stage, were used to construct a nomogram, which showed a concordance index (C-index) of 0.727 in the training cohort and 0.728 in the validation cohort. The model's performance was validated with AUC and calibration curves (training cohort: 1-year AUC: 0.74, 3-year AUC: 0.78, 4-year AUC: 0.80; validation cohort: 1-year AUC: 0.67, 3-year AUC: 0.71, 4-year AUC: 0.72). Kaplan-Meier survival curves illustrated the impact of independent prognostic factors. Conclusions: We developed a nomogram to predict survival in

Indexed as

alcohol consumptionHelicobacter pylori-positive (H. pylori-positive)non-cardia gastric adenocarcinoma (NCGAC)tumor differentiationtumor stage (T stage)

Identifiers

PMID40530114
PMCPMC12170047

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.