ArticleFrontiers in psychiatry2025
The relationship between cognitive function and muscle mass in older adults: a longitudinal study based on CLHLS.
Article in Frontiers in psychiatry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- The Link Between Physical Fitness and Cognitive Function in Vulnerable Low-Income Older Adults from Amazonas, Brazil.Healthcare (Basel, Switzerland) · 2026Article
- Article
- Sarcopenia in the Aging Process: Pathophysiological Mechanisms, Clinical Implications, and Emerging Therapeutic Approaches.International journal of molecular sciences · 2025Review
- Association Between Lymphocyte-High Density Lipoprotein Ratio and Cognitive Impairment in Chinese Older Adults: A Population-Based Cross-Section Study.American journal of Alzheimer's disease and other dementiasArticle
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6 authors.
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Abstract
Background: Sarcopenia is the main cause of disability in an aging society and increases the risk of death in older adults. However, the relationship between cognitive function and muscle mass and the underlying mechanisms are not clear. This study aims to investigate the relationship between cognitive function and muscle mass in the older adults. Methods: This study was based on the Chinese Longitudinal Healthy Longevity Survey (CLHLS), phase III from 2011 to 2018. We analyzed 2536 participants aged ≥60 years. SPSS 27.0 software was used for data screening and statistical analysis, and MPLUS 8.7 and R4.4.2 software were used to construct cross-lag models and restricted cubic splints. Results: In this study, out of 2,536 participants, there were 1,283 males (50.6%) and 1,253 females (49.4%), with an average age of 77.54 ± 8.6 years. Correlation analysis showed that cognitive function was positively correlated with muscle mass in older adults. At all time points ( Conclusion: Muscle mass had a major predictive effect on cognitive trajectory, especially in females. Maintaining ASMI above gender-specific thresholds may help slow cognitive decline, suggesting that muscle mass can serve as an adjustable biomarker for dementia prevention. Longitudinal studies should verify the validity of these thresholds in different populations.
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