Evidence map›Paper›PMID 40530037›Full record

ArticleFrontiers in veterinary science2025

Immune cell profile and metabolic preference following intramuscular lipopolysaccharide injection of highly inbred and advanced intercross genetic lines.

Kayla M Elmore, Susan J Lamont, Elizabeth A Bobeck

Abstract read
In one paragraph

Article in Frontiers in veterinary science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Kayla M ElmoreDepartment of Animal Science, Iowa State University, Ames, IA, United States.
Susan J LamontDepartment of Animal Science, Iowa State University, Ames, IA, United States.
Elizabeth A BobeckDepartment of Animal Science, Iowa State University, Ames, IA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lipopolysaccharide (LPS), a gram-negative bacterial cell wall component commonly used in animal models of inflammation, is also universally found in poultry environments. Documented LPS effects in production animals include reduced feed intake and weight loss; however, research into LPS's impact on cellular metabolism and immune recovery is limited. This study compared baseline and stressed metabolic phenotypes of peripheral blood mononuclear cells (PBMC) from highly inbred genetic lines and examined fuel preference, cell profiles, and C-reactive protein (CRP) expression at baseline and post-LPS injection. Forty birds from 4 genetic lines (Ghs, Line-8, Sp-21.1, and AIL-F) were randomly assigned to 1 of 2 treatments, receiving intramuscular injections of saline or 1 mg/kg BW LPS (

Indexed as

cellular metabolic profileC-reactive proteingenetic lineimmune cell profileimmunometabolic assaylipopolysaccharidepoultry

Identifiers

PMID40530037
PMCPMC12170644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.