Evidence map›Paper›PMID 40529903›Full record

ArticleJournal of orthopaedics2025

Kinematic alignment in total knee arthroplasty restores the native anatomy, with a joint line parallel to the ground on a standing view.

Andrea Pintore, Donato Notarfrancesco, Arnaldo Zara, Francesco Oliva, Filippo Migliorini, Nicola Maffulli

Abstract read
In one paragraph

Article in Journal of orthopaedics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Andrea PintoreDepartment of Medicine, Surgery and Dentistry, University of Salerno, Via S. Allende, Baronissi, 84081, Italy.
Donato NotarfrancescoCasa di Cura Salus, Battipaglia, 84091, Italy.
Arnaldo ZaraCasa di Cura Salus, Battipaglia, 84091, Italy.
Francesco OlivaDepartment of Human Sciences and Promotion of the Quality of Life, San Raffaele Roma Open University, 00166, Rome, Italy.
Filippo MiglioriniDepartment of Trauma and Reconstructive Surgery, University Hospital of Halle, Martin-Luther University Halle-Wittenberg, 06097, Halle (Saale), Germany.
Nicola MaffulliDepartment of Trauma and Orthopaedic Surgery, Faculty of Medicine and Psychology, University la Sapienza, 00185, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Kinematic alignment (KA) total knee arthroplasty (TKA) restores the native alignment of the knee joint. The present study compared the pre-and post-operative limb alignment of patients undergoing KA-TKA. It evaluated joint line orientation and obliquity on weight-bearing radiographs with the ground as reference. Methods: 56 patients treated with KA-TKA from January to December 2022 were prospectively included. The coronal orientation of the TKA was evaluated on pre- and postoperative anteroposterior long-leg weight-bearing radiographs. For each patient, measurements were made of the hip-knee-ankle (HKA) angle, lateral distal femoral angle (LDFA), medial proximal tibial angle (MPTA), arithmetic HKA (aHKA), and joint line obliquity (JLO). Results: The mean LDFA of all patients was 84.6° ± 1.7° pre-operatively and 84.5° ± 1.5° post-operatively (P = 0.06). The mean MPTA of all patients was 83.5° ± 1.6° pre-operatively and 85.1° ± 2.1° post-operatively (P = 0.07). The mean HKA of all patients was 172° ± 2° pre-operatively and 175° ± 2° post-operatively (P = 0.47). The difference in LDFA, MPTA, HKA, JLO and aHKA pre-operatively and post-operatively was not statistically significant. Conclusion: There were no differences in pre- and postoperative radiographic measurements and alignment of the lower limb in patients undergoing KA-TKA, with the joint line orientation parallel to the ground on weight-bearing radiographs in all patients. Longer-term follow-up is necessary to assess the functional outcome and study implant survival of KA-TKA.

Indexed as

AlignmentArthroplastyKinematicKneeMechanicalTotal

Identifiers

PMID40529903
PMCPMC12167787

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.