Evidence map›Paper›PMID 40529877›Full record

ArticleSmall science2025

Experimental and Computational Study of Injectable Iron(III)/Ultrashort Peptide Hydrogels: A Candidate for Ferroptosis-Induced Treatment of Bacterial Infections.

Capucine Loth, Florent Barbault, Cécile Guégan, Flora Lemaire, Christophe Contal, Alain Carvalho, Sophie Hellé, Marie Champion, Halima Kerdjoudj, Delphine Chan-Seng and 2 more

Abstract read
In one paragraph

Article in Small science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Capucine LothUniversité de Strasbourg CNRS Institut Charles Sadron UPR 22 F-67000 Strasbourg France.
Florent BarbaultUniversité Paris Cité CNRS ITODYS F-75013 Paris France.
Cécile GuéganInserm UMR_S 1121 CNRS EMR 7003 Biomaterials and Bioengineering Université de Strasbourg Centre de Recherche en Biomédecine de Strasbourg 1 rue Eugène Boeckel F-67000 Strasbourg France.
Flora LemaireBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691 Université de Reims Champagne Ardenne F-51100 Reims France.
Christophe ContalUniversité de Strasbourg CNRS Institut Charles Sadron UPR 22 F-67000 Strasbourg France.
Alain CarvalhoUniversité de Strasbourg CNRS Institut Charles Sadron UPR 22 F-67000 Strasbourg France.
Sophie HelléInserm UMR_S 1121 CNRS EMR 7003 Biomaterials and Bioengineering Université de Strasbourg Centre de Recherche en Biomédecine de Strasbourg 1 rue Eugène Boeckel F-67000 Strasbourg France.
Marie ChampionInserm UMR_S 1121 CNRS EMR 7003 Biomaterials and Bioengineering Université de Strasbourg Centre de Recherche en Biomédecine de Strasbourg 1 rue Eugène Boeckel F-67000 Strasbourg France.
Halima KerdjoudjBiomatériaux et Inflammation en Site Osseux (BIOS) EA 4691 Université de Reims Champagne Ardenne F-51100 Reims France.
Delphine Chan-SengUniversité de Strasbourg CNRS Institut Charles Sadron UPR 22 F-67000 Strasbourg France.
Lydie PlouxInserm UMR_S 1121 CNRS EMR 7003 Biomaterials and Bioengineering Université de Strasbourg Centre de Recherche en Biomédecine de Strasbourg 1 rue Eugène Boeckel F-67000 Strasbourg France.
Fouzia BoulmedaisUniversité de Strasbourg CNRS Institut Charles Sadron UPR 22 F-67000 Strasbourg France.ORCID https://orcid.org/0000-0002-4934-9276

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Injectable hydrogels are promising candidates as local drug delivery platforms for the treatment of infected wounds. Self-assembled small peptide hydrogels are of interest due to their high biocompatibility, degradability, and ease of synthesis. This study describes the formation of an injectable hydrogel based on the self-assembly of Fmoc-FFpY (Fmoc: fluorenylmethoxycarbonyl, F: phenylalanine, pY: tyrosine phosphate) triggered by electrostatic interactions in the presence of Fe

Indexed as

antibacterialFmoc‐FFmolecular dynamicsreactive oxygen speciessiderophores

Identifiers

PMID40529877
PMCPMC12168595

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.