Evidence map›Paper›PMID 40529782›Full record

ArticleJournal of thoracic disease2025

Prognosis of critically ill immunocompromised patients with COVID-19 admitted for acute respiratory failure: a retrospective propensity score analysis.

Océane Bernard de Lajartre, Alexia Le Corre, Anaelle Bichon, Nicolas Terzi, Arnaud Gacouin, Adel Maamar, Jean-Marc Tadie

Abstract read
In one paragraph

Article in Journal of thoracic disease, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Océane Bernard de LajartreDepartment of Infectious Diseases and Intensive Care Unit, CHU Rennes, Rennes, France.
Alexia Le CorreDepartment of Infectious Diseases and Intensive Care Unit, CHU Rennes, Rennes, France.
Anaelle BichonDepartment of Infectious Diseases and Intensive Care Unit, CHU Rennes, Rennes, France.
Nicolas TerziDepartment of Infectious Diseases and Intensive Care Unit, CHU Rennes, Rennes, France.
Arnaud GacouinDepartment of Infectious Diseases and Intensive Care Unit, CHU Rennes, Rennes, France.
Adel MaamarDepartment of Infectious Diseases and Intensive Care Unit, CHU Rennes, Rennes, France.
Jean-Marc TadieDepartment of Infectious Diseases and Intensive Care Unit, CHU Rennes, Rennes, France.ORCID https://orcid.org/0000-0002-7604-4849

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Since the introduction of coronavirus disease 2019 (COVID-19) vaccination, the proportion of immunocompromised patients among critically ill individuals admitted to the intensive care unit (ICU) for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pneumonia seems to have increased significantly. However, data on this specific critically ill population remain limited. The aim of our study is to explore the impact of immunocompromised status on ICU outcomes in COVID-19 patients admitted for acute respiratory failure (ARF). Methods: In this retrospective study, data from adult patients admitted for ARF-related to SARS-CoV-2 pneumonia were collected. To study the impact of immunocompromised status, immunocompromised and non-immunocompromised patients were matched using propensity scores. A Cox-proportional hazard model was used to determine whether immunocompromised status during the ICU stay was associated with ICU mortality. Results: Between March 2021, the time of admission of the first vaccinated patients, and December 2022, we identified 294 patients (220 non-immunocompromised, 74 immunocompromised). The immunocompromised group had a greater risk of mortality in the ICU (31.1% Conclusions: After adjustment for prognostic variables, the immunocompromised status of patients admitted to the ICU for SARS-CoV-2-related ARF was not associated with increased mortality, despite a significantly longer ICU stay and a greater rate of ICU acquired infections.

Indexed as

acute respiratory failure (ARF)Coronavirus disease 2019 (COVID-19)immunocompromisedintensive care unit (ICU)mortality

Identifiers

PMID40529782
PMCPMC12170114

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.