ArticleAmerican heart journal plus : cardiology research and practice2025
Impact of aortic valve calcification volume on left ventricular systolic function in patients with severe aortic stenosis undergoing transcatheter aortic valve implantation.
Article in American heart journal plus : cardiology research and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
2 citing papers in PubMed.
- Critique of aortic valve calcification's impact on LV recovery after TAVI.American heart journal plus : cardiology research and practice · 2025Article
- Association Between AI-derived Thoracic Calcium Volume and Aortic Valve Calcification Quantified by Agatston Scoring.In vivo (Athens, Greece)Article
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Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Aortic valve calcification (AVC) has been linked to negative cardiac outcomes in patients with aortic stenosis (AS). Given the limited understanding of its specific contributions, we aimed to investigate the interaction between AVC and the left ventricular (LV) systolic function in patients with severe AS and LV systolic dysfunction who underwent transcatheter aortic valve implantation (TAVI). Materials and methods: An observational study of 75 patients with severe AS and LV ejection fraction (EF) ≤ 50 % who underwent TAVI. AVC volume was determined by ECG-gated contrast-enhanced multidetector computed tomography (MDCT) using specific software (3Mensio Structural Heart version 10.4, Pie Medical Imaging, Maastricht, the Netherlands). Patients were categorized into two groups based on LV systolic function recovery 30 days after TAVI defined by ≥10 % absolute increase in LVEF compared to baseline. Results: AVC volume showed a statistically significant negative correlation with the baseline LVEF ( Conclusion: AVC volume has a paradoxical association with LV systolic function. Patients with a higher AVC volume had a more depressed baseline LV systolic function and a greater likelihood of LV systolic function recovery after TAVI.
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