Evidence map›Paper›PMID 40529233›Full record

ArticleInfection and drug resistance2025

Molecular Characteristics and Antimicrobial Resistance of Linezolid-Resistant

Shan Zhou, Ke Zhou, Peihong Yang, Meijuan Kong, Hao Liu, Rui Zhang, Zheng Hou, Jiayun Liu

Abstract read
In one paragraph

Article in Infection and drug resistance, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Linezolid MIC creep among clinically significantFrontiers in antibiotics · 2026
    Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Shan Zhou *Department of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi, 710032, People's Republic of China.
Ke Zhou *Department of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi, 710032, People's Republic of China.ORCID 0000-0002-8588-8904
Peihong Yang *Department of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi, 710032, People's Republic of China.
Meijuan KongDepartment of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi, 710032, People's Republic of China.
Hao LiuDepartment of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi, 710032, People's Republic of China.
Rui ZhangDepartment of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi, 710032, People's Republic of China.
Zheng HouInstitute of Medical Research, Northwestern Polytechnical University, Xi'an, Shanxi, 710129, People's Republic of China.ORCID 0000-0002-0358-7869
Jiayun LiuDepartment of Clinical Laboratory, Xijing Hospital, Air Force Medical University, Xi'an, Shanxi, 710032, People's Republic of China.ORCID 0000-0003-0293-247X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: This study examines the distribution of pathogens and the characteristics of linezolid-resistant Methods: Identification and initial antimicrobial susceptibility testing were conducted using the VITEK2 compact system. Broth microdilution method (BMD) to confirm linezolid-resistant isolates. The results were interpreted according to the Clinical and Laboratory Standards Institute (CLSI) guideline. Polymerase chain reaction (PCR) screening identified linezolid-resistance-related genes and molecular typing loci. Results: From 2012 to 2022, 2049 clinical isolates were collected, with Conclusion: Our findings highlight the importance of accurate susceptibility testing and proactive monitoring of LRSA in the treatment of chronic OAIs to mitigate potential therapeutic challenges.

Indexed as

antimicrobial resistancelinezolidosteoarticular infectionsStaphylococcus aureus

Identifiers

PMID40529233
PMCPMC12170810

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.