ArticleACS medicinal chemistry letters2025
Novel Desamide Isotryptamine Tetracycles as 5‑HT2C Agonists for Treating Brain Disorders.
Article in ACS medicinal chemistry letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
8 citing papers in PubMed.
- The Emergence of Isotryptamine Analogs as Novel Serotonergic Agents with Psychotherapeutic Potential.ACS pharmacology & translational science · 2026Review
- Novel Mixed Serotonin Receptor Binder Compounds as 5‑HT2C Agonists for Treating Psychotic Disorders.ACS medicinal chemistry letters · 2025Article
- Novel Azepinoindoles as 5‑HT2C Agonists for Treating Depression, Drug Addiction, Alcoholism, PTSD, and Neuropathic Pain.ACS medicinal chemistry letters · 2025Article
- Novel 3‑(2-(Aminoethyl)-indol-4-ol Derivatives as 5‑HT2C Agonists for Treating Depression, Alcoholism, Drug Addiction, PTSD, and Seizure Disorders.ACS medicinal chemistry letters · 2025Article
- Novel 5,6-Dihydro-4H-pyrrolo[3,2,1-ij]quinoline-5-yl Amine Compounds as 5‑HT2C Agonists for Treating Psychotic Disorders, Namely, Personality Disorders and Eating Disorders.ACS medicinal chemistry letters · 2025Article
- Novel Benzofuran and Benzothiophene Psychedelic Psychoplastogens as 5‑HT2C Agonists for Treating Neurological Diseases.ACS medicinal chemistry letters · 2025Article
- Novel Phenoxy and Benzyloxy Substituted Psychedelic Psychoplastogens as 5‑HT2C Agonists for Treating Neurological Diseases.ACS medicinal chemistry letters · 2025Article
- Novel Tricyclic Psychedelic Psychoplastogens as 5‑HT2C Agonists for Treating Neurological Diseases.ACS medicinal chemistry letters · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
1 author.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Provided herein are novel desamide isotryptamine tetracycles as 5-HT2C agonists, pharmaceutical compositions, use of such compounds in treating brain disorders, and processes for preparing such compounds.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.