Evidence map›Paper›PMID 40529066›Full record

ArticleACS medicinal chemistry letters2025

Suzuki-Miyaura Coupling of Pinacolboronic Esters Catalyzed by a Well-Defined Palladium

Aleksei A Logvinov, Geert Rombouts, Matthieu Jouffroy, Steven P Nolan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Access to Pyrazolo[1,5-Organic letters · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aleksei A LogvinovDepartment of Chemistry and Centre for Sustainable Chemistry, Ghent University, Campus Sterre, Krijgslaan 281-S3, 9000 Ghent, Belgium.ORCID https://orcid.org/0000-0002-0471-0099
Geert RomboutsGlobal Discovery Chemistry, Janssen Pharmaceutica NV, a Johnson & Johnson Company, 2340 Beerse, Belgium.ORCID https://orcid.org/0009-0005-8400-1039
Matthieu JouffroyChemical Process R&D, Discovery Process Research, Janssen Pharmaceutica N.V., Turnhoutseweg 30, 2340 Beerse, Belgium.ORCID https://orcid.org/0000-0003-4478-2502
Steven P NolanDepartment of Chemistry and Centre for Sustainable Chemistry, Ghent University, Campus Sterre, Krijgslaan 281-S3, 9000 Ghent, Belgium.ORCID https://orcid.org/0000-0001-9024-2035

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a versatile synthetic method for coupling heteroaryl chlorides and bromides with (hetero)-aryl pinacolboronic esters of pharmaceutical interest at low catalyst loading of a well-defined palladium-NHC catalyst providing products in good to high isolated yield and purity in short reaction time. The method displays remarkably broad applicability with both 5- and 6-membered heterocycles.

Indexed as

HeterocyclesN-Heterocyclic CarbenesSuzuki−Miyaura Coupling

Identifiers

PMID40529066
PMCPMC12169495

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.