Evidence map›Paper›PMID 40529064›Full record

ArticleACS medicinal chemistry letters2025

Selective Inhibition of Carbonic Anhydrase IX and XII by Natural Coumarin Coladonin and Its Derivatives: Promising Antimelanoma and Antiglioblastoma Agents.

Muhamad Mustafa, Wiem Baccari, Alessio Nocentini, Maria Luisa Massardi, Michael Smietana, Eslam M Abbass, Ilyes Saidi, Mansour Znati, Hichem Ben Jannet, Roberto Ronca and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS medicinal chemistry letters, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Muhamad MustafaIBMM, Univ Montpellier, CNRS, ENSCM, Montpellier, 34095, France.ORCID https://orcid.org/0000-0002-1384-7556
Wiem BaccariLaboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11ES39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Monastir 5000, Tunisia.
Alessio NocentiniDepartment of NEUROFARBA - Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, 50019 Sesto Fiorentino, Firenze 50019, Italy.ORCID https://orcid.org/0000-0003-3342-702X
Maria Luisa MassardiDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Michael SmietanaIBMM, Univ Montpellier, CNRS, ENSCM, Montpellier, 34095, France.ORCID https://orcid.org/0000-0001-8132-7221
Eslam M AbbassIBMM, Univ Montpellier, CNRS, ENSCM, Montpellier, 34095, France.ORCID https://orcid.org/0000-0002-3245-1653
Ilyes SaidiLaboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11ES39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Monastir 5000, Tunisia.
Mansour ZnatiLaboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11ES39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Monastir 5000, Tunisia.
Hichem Ben JannetLaboratory of Heterocyclic Chemistry, Natural Products and Reactivity (LR11ES39), Team: Medicinal Chemistry and Natural Products, Faculty of Science of Monastir, University of Monastir, Monastir 5000, Tunisia.
Roberto RoncaDepartment of Molecular and Translational Medicine, University of Brescia, 25123 Brescia, Italy.
Claudiu T SupuranDepartment of NEUROFARBA - Section of Pharmaceutical and Nutraceutical Sciences, University of Florence, 50019 Sesto Fiorentino, Firenze 50019, Italy.ORCID https://orcid.org/0000-0003-4262-0323
Jean-Yves WinumIBMM, Univ Montpellier, CNRS, ENSCM, Montpellier, 34095, France.ORCID https://orcid.org/0000-0003-3197-3414

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coladonin, a natural sesquiterpene coumarin ether isolated from

Indexed as

Anticancer compoundsCarbonic anhydrasesColadoninCoumarinGlioblastomaHypoxiaMelanoma

Identifiers

PMID40529064
PMCPMC12169602

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.