Evidence map›Paper›PMID 40528990›Full record

ReviewFundamental research2025

Role of artificial intelligence in revolutionizing drug discovery.

Ashfaq Ur Rehman, Mingyu Li, Binjian Wu, Yasir Ali, Salman Rasheed, Sana Shaheen, Xinyi Liu, Ray Luo, Jian Zhang

Abstract readReview
In one paragraph

Review in Fundamental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 39 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
39citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

39 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  4. Mechanistic Insights into the Role of Artificial Intelligence and Machine Learning in the Diagnosis and Management of Multiple Sclerosis.Pathophysiology : the official journal of the International Society for Pathophysiology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Ashfaq Ur RehmanMedicinal Chemistry and Bioinformatics Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Mingyu LiMedicinal Chemistry and Bioinformatics Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Binjian WuMedicinal Chemistry and Bioinformatics Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Yasir AliInstitute of Chemistry, Slovak Academy of Sciences, 845 38 Bratislava, Slovakia.
Salman RasheedNational Center for Bioinformatics, Quaid-e-Azam University, Islamabad 44000, Pakistan.
Sana ShaheenKey Department of Biochemistry, Abdul Wali Khan University Mardan, Khyber-Pakhtunkhwa 23200, Pakistan.
Xinyi LiuMedicinal Chemistry and Bioinformatics Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.
Ray LuoDepartments of Molecular Biology and Biochemistry, University of California Irvine, Irvine, CA 92697, United States.
Jian ZhangMedicinal Chemistry and Bioinformatics Center, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The application of artificial intelligence (AI) in medicine, particularly through machine learning (ML), marked a significant progression in drug discovery. AI acts as a powerful catalyst in narrowing the gap between disease understanding and the identification of potential therapeutic agents. This review provides an inclusive summary of the latest advancements in AI and its application in drug discovery. We examine the various stages of the drug discovery process, starting from disease identification and encompassing diagnosis, target identification, screening, and lead discovery. AI's capability to analyze extensive datasets and discern patterns is essential in these stages, enhancing predictions and efficiencies in disease identification, drug discovery, and clinical trial management. The role of AI in expediting drug development is emphasized, highlighting its potential to analyze vast data volumes, thus reducing the time and costs associated with new drug market introduction. The importance of data quality, algorithm training, and ethical considerations, especially in patient data handling during clinical trials, is addressed. By considering these factors, AI promises to transform drug development, offering significant benefits to patients and society.

Indexed as

Artificial intelligenceDisease identificationDrug designDrug discoveryMachine learning

Identifiers

PMID40528990
PMCPMC12167903

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.