Evidence map›Paper›PMID 40528972›Full record

ArticleFundamental research2025

Engineered in-situ-forming biomimetic hydrogel with self-regulated immunostimulatory capacity promotes postoperative tumor treatment.

Zhuo Cheng, Yan Hu, Yingqi Liu, Xuan Wang, Rui Xue, Kaiyong Cai, Liqi Li, Menghuan Li, Zhong Luo

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Fundamental research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Zhuo ChengSchool of Life Science, Chongqing University, Chongqing 400044, China.
Yan HuKey Laboratory of Biorheological Science and Technology, Ministry of Education, The National "111" Project for Biomechanics and Tissue Repair Engineering, Chongqing University, Chongqing 400044, China.
Yingqi LiuSchool of Life Science, Chongqing University, Chongqing 400044, China.
Xuan WangSchool of Life Science, Chongqing University, Chongqing 400044, China.
Rui XueSchool of Life Science, Chongqing University, Chongqing 400044, China.
Kaiyong CaiKey Laboratory of Biorheological Science and Technology, Ministry of Education, The National "111" Project for Biomechanics and Tissue Repair Engineering, Chongqing University, Chongqing 400044, China.
Liqi LiDepartment of General Surgery, Xinqiao Hospital, Army Medical University, Chongqing 400037, China.
Menghuan LiSchool of Life Science, Chongqing University, Chongqing 400044, China.
Zhong LuoSchool of Life Science, Chongqing University, Chongqing 400044, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Post-resection tumors with microscopic foci and immunosuppressive microenvironments have high risk of recurrence and metastasis but respond poorly to various therapies. Herein, we propose a biomimetic hydrogel as a biocompatible, biodegradable and bioadhesive postoperative dressing that could be formed in situ by NaIO

Indexed as

Cooperative ferroptosis-immunotherapyInjectable in-situ forming hydrogelMicroenvironment remodelingPostoperative tumor therapySupramolecular bioresponsive prodrug

Identifiers

PMID40528972
PMCPMC12167896

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.