Evidence map›Paper›PMID 40528942›Full record

ArticleBJUI compass2025

Mental well-being in prostate cancer: A multi-institutional prospective cohort study.

Oliver Brunckhorst, Jaroslaw Liszka, Callum James, Jack B Fanshawe, Mohamed Hammadeh, Robert Thomas, Shahid Khan, Matin Sheriff, Gordon Muir, Hashim U Ahmed and 4 more

Registry-linked trialAbstract read
In one paragraph

Article in BJUI compass, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04647474 (A Prospective and Longitudinal Cohort Study Assessing Mental wellbeIng and Quality of Life in Prostate Cancer - the MIND-P Study), which is not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04647474 completednot on this map

A Prospective and Longitudinal Cohort Study Assessing Mental wellbeIng and Quality of Life in Prostate Cancer - the MIND-P Study

TypeobservationalSponsorKing's College LondonRan2021 to 2023Enrolled300ConditionsProstate Cancer
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Oliver BrunckhorstMRC Centre for Transplantation Guy's Hospital Campus, King's College London, King's Health Partners London UK.ORCID https://orcid.org/0000-0002-2073-922X
Jaroslaw LiszkaMRC Centre for Transplantation Guy's Hospital Campus, King's College London, King's Health Partners London UK.
Callum JamesMRC Centre for Transplantation Guy's Hospital Campus, King's College London, King's Health Partners London UK.
Jack B FanshaweDepartment of Psychiatry University of Oxford Oxford UK.ORCID https://orcid.org/0000-0003-3732-217X
Mohamed HammadehDepartment of Urology Queen Elizabeth Hospital, Lewisham and Greenwich NHS Trust London UK.
Robert ThomasThe Primrose Oncology Unit Bedfordshire Hospitals NHS Foundation Trust Bedford UK.
Shahid KhanDepartment of Urology East Surrey Hospital, Surrey and Sussex Healthcare NHS Trust Redhill UK.
Matin SheriffDepartment of Urology Medway NHS Foundation Trust Gillingham UK.
Gordon MuirDepartment of Urology King's College Hospital NHS Foundation Trust London UK.
Hashim U AhmedImperial Prostate, Division of Surgery, Department of Surgery and Cancer Imperial College London London UK.ORCID https://orcid.org/0000-0003-1674-6723
Mieke Van HemelrijckTranslational Oncology and Urology Research (TOUR), School of Cancer and Pharmaceutical Sciences King's College London London UK.ORCID https://orcid.org/0000-0002-7317-0858
Robert StewartKing's College London Institute of Psychiatry, Psychology and Neuroscience London UK.ORCID https://orcid.org/0000-0002-4435-6397
Prokar DasguptaMRC Centre for Transplantation Guy's Hospital Campus, King's College London, King's Health Partners London UK.ORCID https://orcid.org/0000-0001-8690-0445
Kamran AhmedMRC Centre for Transplantation Guy's Hospital Campus, King's College London, King's Health Partners London UK.ORCID https://orcid.org/0000-0002-5135-9211

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To investigate the patient, treatment and oncological prognostic factors for multiple mental well-being outcomes in prostate cancer. Patient and Methods: The MIND-P study was a multi-institutional prospective cohort study recruiting newly diagnosed prostate cancer patients for 12 months post-diagnosis across eight centres. Periodic data collection evaluated mental, physical and social well-being measures incorporating five mental well-being outcomes selected based on prior research as important measures in patients with prostate cancer. This included depression, anxiety, fear of recurrence, body image, and masculinity. Treatment, patient, and oncological prognostic factors for developing significant well-being symptoms were evaluated along with symptom trajectories. Results: Of 300 patients recruited, 13.7% and 11.0% developed depression or anxiety symptoms, with 45.0% developing at least one significant mental well-being symptom. Those undergoing hormone monotherapy had higher depression scores from 6 months post-diagnosis (all Conclusion: A high incidence of multiple mental well-being issues was identified post-diagnosis, highlighting their individual importance during follow-up. Baseline mental and functional symptoms, a previous psychiatric history and stage at diagnosis appear to be particularly important prognostic factors for the development of significant symptoms. A comprehensive initial biopsychosocial assessment incorporating these could identify high-risk patients for improved monitoring and subsequent support. ClinicalTrials.gov number - NCT04647474.

Indexed as

anxietybody imagedepressionmasculinityprostate cancerquality of lifesurvivorship

Identifiers

PMID40528942
PMCPMC12171242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.